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Pregled bibliografske jedinice broj: 154702

Cost analysis of low-dose rocuronium for day-case tonsillectomy in children


Bartolek, Dubravka; Fučkar, Božidar; Munitić, Ante; Rak, Ivica; Borčić, Vinko; Znaor, Tin
Cost analysis of low-dose rocuronium for day-case tonsillectomy in children // Abstract of The 76th Clinical and Scientific Congress of International Anesthesia Research Society (IARS 2002) ; u: Anesthesia & Analgesia 94 (2002) (S54) 1-350
San Diego, Kalifornija, SAD, 2002. str. S-19 (poster, međunarodna recenzija, sažetak, znanstveni)


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Naslov
Cost analysis of low-dose rocuronium for day-case tonsillectomy in children

Autori
Bartolek, Dubravka ; Fučkar, Božidar ; Munitić, Ante ; Rak, Ivica ; Borčić, Vinko ; Znaor, Tin

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, znanstveni

Izvornik
Abstract of The 76th Clinical and Scientific Congress of International Anesthesia Research Society (IARS 2002) ; u: Anesthesia & Analgesia 94 (2002) (S54) 1-350 / - , 2002, S-19

Skup
Clinical and Scientific Congress of International Anesthesia Research Society (76 ; 2002)

Mjesto i datum
San Diego, Kalifornija, SAD, 16.-20.03.2002

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
rocuronium; day case surgery; tonsillectomy; paediatric anaesthesia

Sažetak
Over the past few years there has been an increase of elective day-case tonsillectomy in children. Rocuronium and vecuronium are neuromuscular blockers used commonly in pediatric anesthesia. We evaluated the cost analysis following s low-dose rocuronium (0.45 mg/kg) as the intubating conditions, onset time, duration and spontaneous recovery of neuromuscular block in children for day-case tonsillectomy with mean duration under thirty minutes. Ninety children of ASA I or II status were studied in the prospective, randomized, double-blinded study. The Etic Committee of the Clinical Hospital Merkur approved protocol of the study. Anesthesia was induced with propofol 2.5 mg/kg. In thirty children muscle relaxation was achieved with vecuronium (0.1 mg/kg)(V)or rocuronium (0.6 mg(kg))(R) in standard or in low-dose of rocuronium (0.45 mg/kg)(LR). Anesthesia was maintained by a continuous infusion of propofol (0.1 mg/kg min) and alfentanyl (0.0015 mg/kg min) with 50% oxygen in nitrous oxide. Neuromuscular transmission was monitored by means of acceleromyography with supramaximal train-of-four stimulation of the ulnar nerve with frequency of 1 Hz. A cost analysis was performed. Differences between three groups were evaluated by ANOVA and the Kruskal-Wallis test. Then a multiple linear regresion analysis was conducted. A P-value beloe 0.05 was considered as statistically significant. Multiple regression analysis revealed that intubating dose of vecuronium in standard dose for child (66 pounds) was on average cheaper per surgery than rocuronium (R=2.7, V=1.9 Euro. There was no significant difference in cost between low-dosis of rocuronium and vecuronium in standard dosis (LR=1.8, V=1.9 Euro). Although the onset time was significantly longer after a low-dose rocuronium (LR=3.1+/-0.4 ; R=1.3+/-0.4 ; V=2.2+/- min) no difference was found in the intubating conditions. Clinical duration of the block (T25) was significantly shorter after a low-dose rocuronium (LR=10.9+/- ; R=18.8+/-1.0 ; V22.7+/-4.1 min). Low-dose rocuronium in children was more economical for elective procedures in day-case tonsillectomy in children than standard dose. It results in a long onset time and shorter duration of the neuromuscular block without significantly changing intubating conditions.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti



POVEZANOST RADA


Ustanove:
Klinička bolnica "Merkur"

Profili:

Avatar Url Dubravka Bartolek Hamp (autor)

Avatar Url Tin Znaor (autor)

Avatar Url Ante Munitić (autor)


Citiraj ovu publikaciju

Bartolek, Dubravka; Fučkar, Božidar; Munitić, Ante; Rak, Ivica; Borčić, Vinko; Znaor, Tin
Cost analysis of low-dose rocuronium for day-case tonsillectomy in children // Abstract of The 76th Clinical and Scientific Congress of International Anesthesia Research Society (IARS 2002) ; u: Anesthesia & Analgesia 94 (2002) (S54) 1-350
San Diego, Kalifornija, SAD, 2002. str. S-19 (poster, međunarodna recenzija, sažetak, znanstveni)
Bartolek, D., Fučkar, B., Munitić, A., Rak, I., Borčić, V. & Znaor, T. (2002) Cost analysis of low-dose rocuronium for day-case tonsillectomy in children. U: Abstract of The 76th Clinical and Scientific Congress of International Anesthesia Research Society (IARS 2002) ; u: Anesthesia & Analgesia 94 (2002) (S54) 1-350.
@article{article, year = {2002}, pages = {S-19-S-20}, keywords = {rocuronium, day case surgery, tonsillectomy, paediatric anaesthesia}, title = {Cost analysis of low-dose rocuronium for day-case tonsillectomy in children}, keyword = {rocuronium, day case surgery, tonsillectomy, paediatric anaesthesia}, publisherplace = {San Diego, Kalifornija, SAD} }
@article{article, year = {2002}, pages = {S-19-S-20}, keywords = {rocuronium, day case surgery, tonsillectomy, paediatric anaesthesia}, title = {Cost analysis of low-dose rocuronium for day-case tonsillectomy in children}, keyword = {rocuronium, day case surgery, tonsillectomy, paediatric anaesthesia}, publisherplace = {San Diego, Kalifornija, SAD} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE





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