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Pregled bibliografske jedinice broj: 153568

Nitrosyl Haemoglobin: The NO-Spin as a Relaxation Probe in the Solvent-Proton Magnetic Resonance Experiment Demonstrating the Phosphate-Induced Widening of the Haem-Pocket


Benko, Bojan; Vuk-Pavlović, Stanimir
Nitrosyl Haemoglobin: The NO-Spin as a Relaxation Probe in the Solvent-Proton Magnetic Resonance Experiment Demonstrating the Phosphate-Induced Widening of the Haem-Pocket // Biochemical and biophysical research communications, 71 (1976), 4; 1303-1307 (međunarodna recenzija, članak, znanstveni)


Naslov
Nitrosyl Haemoglobin: The NO-Spin as a Relaxation Probe in the Solvent-Proton Magnetic Resonance Experiment Demonstrating the Phosphate-Induced Widening of the Haem-Pocket

Autori
Benko, Bojan ; Vuk-Pavlović, Stanimir

Izvornik
Biochemical and biophysical research communications (0006-291X) 71 (1976), 4; 1303-1307

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Haemoglobin; Inositol hexaphosphate; Nitric oxide; Proton magnetic relaxation;

Sažetak
This communication presents evidence that nitric oxide bound to ferrous haem-iron of haemoglobin is a powerful relaxation probe in the solvent-proton magnetic resonance experiments. When such an experiment is applied to the interaction of human haemoglobin with inositol hexaphosphate, it shows that phosphate increases the solvent-dynamics in the haem-pockets, consistent with their widening. Some implications of these findings are discussed here.

Izvorni jezik
Engleski

Znanstvena područja
Fizika, Kemija, Biologija



POVEZANOST RADA


Ustanove
Imunološki zavod d.d.

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE