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Pregled bibliografske jedinice broj: 147681

Tumor suppresor gene E-cadherin and its role in normal and malignant cells


Pećina-Šlaus, Nives
Tumor suppresor gene E-cadherin and its role in normal and malignant cells // Cancer cell international, 23 (2003), 3; 1-7 (međunarodna recenzija, pregledni rad, znanstveni)


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Naslov
Tumor suppresor gene E-cadherin and its role in normal and malignant cells

Autori
Pećina-Šlaus, Nives

Izvornik
Cancer cell international (1475-2867) 23 (2003), 3; 1-7

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, pregledni rad, znanstveni

Ključne riječi
E-cadherin; CDH1; cell adhesion; wnt signalling

Sažetak
E-cadherin tumor suppressor genes are particularly active area of research in development and tumorigenesis. The calcium-dependent interactions among E-cadherin molecules are critical for the formation and maintenance of adherent junctions in areas of epithelial cell-cell contact. Loss of E-cadherin-mediated-adhesion characterises the transition from benign lesions to invasive, metastatic cancer. Nevertheless, there is evidence that E-cadherins may also play a role in the wnt signal transduction pathway, together with other key molecules involved in it, such as beta-catenins and adenomatous poliposis coli gene products. The structure and function of E-cadherin, gene and protein, in normal as well as in tumor cells are reviewed in this paper.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti



POVEZANOST RADA


Projekti:
0108215

Ustanove:
Medicinski fakultet, Zagreb

Profili:

Avatar Url Nives Pećina-Šlaus (autor)

Citiraj ovu publikaciju

Pećina-Šlaus, Nives
Tumor suppresor gene E-cadherin and its role in normal and malignant cells // Cancer cell international, 23 (2003), 3; 1-7 (međunarodna recenzija, pregledni rad, znanstveni)
Pećina-Šlaus, N. (2003) Tumor suppresor gene E-cadherin and its role in normal and malignant cells. Cancer cell international, 23 (3), 1-7.
@article{article, author = {Pe\'{c}ina-\v{S}laus, N.}, year = {2003}, pages = {1-7}, keywords = {E-cadherin, CDH1, cell adhesion, wnt signalling}, journal = {Cancer cell international}, volume = {23}, number = {3}, issn = {1475-2867}, title = {Tumor suppresor gene E-cadherin and its role in normal and malignant cells}, keyword = {E-cadherin, CDH1, cell adhesion, wnt signalling} }
@article{article, author = {Pe\'{c}ina-\v{S}laus, N.}, year = {2003}, pages = {1-7}, keywords = {E-cadherin, CDH1, cell adhesion, wnt signalling}, journal = {Cancer cell international}, volume = {23}, number = {3}, issn = {1475-2867}, title = {Tumor suppresor gene E-cadherin and its role in normal and malignant cells}, keyword = {E-cadherin, CDH1, cell adhesion, wnt signalling} }

Časopis indeksira:


  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
  • Scopus


Uključenost u ostale bibliografske baze podataka:


  • CA Search (Chemical Abstracts)
  • EMBASE (Excerpta Medica)
  • Scopus





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