Crystal structures, circular dichroism spectra and absolute configurations of some L-ascorbic acid derivatives (CROSBI ID 104524)
Prilog u časopisu | izvorni znanstveni rad | međunarodna recenzija
Podaci o odgovornosti
Wittine, Karlo ; Gazivoda, Tatjana ; Markuš, Marko ; Mrvoš-Sermek, Draginja ; Hergold-Brundić, Antonija ; Cetina, Mario ; Žiher, Dinko ; Gabelica, Vesna ; Mintas, Mladen ; Raić-Malić, Silvana
engleski
Crystal structures, circular dichroism spectra and absolute configurations of some L-ascorbic acid derivatives
Chiral 2, 3-O, O-dibenzyl ethers of L-ascorbic acid with 4-(5, 6-epoxy)- (4) and 6-O-tosyl- (8) functional groups were studied by X-ray crystallography and circular dichroism (CD) spectroscopy. The stereostructure of 2, 3-O, O-dibenzyl-5, 6-isopropylidene-L-ascorbic acid (6) and 8 was determined by X-ray crystal structure analysis. Comparison of the CD-spectra of 4 and 8 with the CD-spectra of their synthetic precursors (2-3, 5-7) and L-ascorbic acid (1) itself, as well as crystal structures of 6 and 8 permitted to deduce the absolute configuration of 4. Thus, the chiral atoms C-4 and C-5 in 4 have R- and S- configurations, which is consistent with the configuration of 1.
L-ascorbic acid derivatives ; single crystal X-ray diffraction ; circular dichroism spectroscopy ; Cotton effect
nije evidentirano
nije evidentirano
nije evidentirano
nije evidentirano
nije evidentirano
nije evidentirano
Podaci o izdanju
687 (1-3)
2004.
101-106
objavljeno
0022-2860
1872-8014
10.1016/j.molstruc.2003.09.019