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Novel cyano- and amidino-substituted styrylbenzothiazoles and their biological activity (CROSBI ID 494795)

Prilog sa skupa u zborniku | sažetak izlaganja sa skupa

Ćaleta, Irena ; Karminski-Zamola, Grace ; Grdiša, Mira ; Pavelić, Krešimir Novel cyano- and amidino-substituted styrylbenzothiazoles and their biological activity // 13th European simposium on organic chemistry : programme & abstracts / Šunjić, Vitomir (ur.). Zagreb, 2003. str. 374-374

Podaci o odgovornosti

Ćaleta, Irena ; Karminski-Zamola, Grace ; Grdiša, Mira ; Pavelić, Krešimir

engleski

Novel cyano- and amidino-substituted styrylbenzothiazoles and their biological activity

A large number of benzothiazole derivatives are of considerable biological and chemical interest. Their pharmaceutical and agrochemical applications are of particular relevance. In order to find a new biologically active benzothiazole compounds we prepared in the multistep synthesis a serie of new styrylbenzothiazole compounds 1-9 starting from 6-cyano-2-methylbenzothiazole or 2-methylbenzothiazole and corresponding benzaldehydes. Cyano-derivatives of styrylbenzothiazoles 1-3 were converted by Pinner reaction into the corresponding amidine hydrochlorides 4-9. All styrylbenzothiazole compounds were tested on their antitumor activity. All compounds were characterized by means of IR, 1H- and 13C-NMR spectroscopy and elemental analysis.

styrylbenzothiazoles; amidines; biological activity

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Podaci o prilogu

374-374.

2003.

objavljeno

Podaci o matičnoj publikaciji

13th European simposium on organic chemistry : programme & abstracts

Šunjić, Vitomir

Zagreb:

Podaci o skupu

European simposium on organic chemistry (13 ; 2003)

poster

10.09.2003-15.09.2003

Cavtat, Hrvatska; Dubrovnik, Hrvatska

Povezanost rada

Kemija