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Pregled bibliografske jedinice broj: 13835

Structural characterization and auxin properties of dichlorinated indole-3-acetic acids


Antolić, Snježana; Salopek, Branka; Kojić-Prodić, Biserka; Magnus, Volker; Cohen, Jerry D.
Structural characterization and auxin properties of dichlorinated indole-3-acetic acids // Plant growth regulation, 27 (1999), 1; 21-31 (međunarodna recenzija, članak, znanstveni)


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Naslov
Structural characterization and auxin properties of dichlorinated indole-3-acetic acids

Autori
Antolić, Snježana ; Salopek, Branka ; Kojić-Prodić, Biserka ; Magnus, Volker ; Cohen, Jerry D.

Izvornik
Plant growth regulation (0167-6903) 27 (1999), 1; 21-31

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
dichlorinated indole-3-acetic acid; auxin; structural characterization; biological activity; Avena sativa straight growth test

Sažetak
The dichlorinated indole-3-acetic acids: 4, 5-Cl2-IAA, 4, 6-Cl2-IAA, 4, 7-Cl2-IAA, 5, 6-Cl2-IAA, 5, 7-Cl2-IAA and 6, 7-Cl2-IAA were synthesized and characterized by X-ray structure analysis to unambiguously identify the substances for bioassays required to establish structure activity relationships of auxins and their analogues. Straight-growth tests were performed on Avena sativa coleoptiles to correlate their auxin activity with molecular properties which could reveal information on the topology of the auxin binding site. Structure/activity correlations revealed that the 5, 6-Cl2-IAA molecule, by virtue of its size, fits particularly well into the active site cavity of the receptor protein. The main contact of the substrate or inhibitor in the receptor active site via the carboxylic group determines their orientation in the active site cavity. As a consequence, the 5, 6-substituted sites protrude into the widest part of the active site, whereas the 7-, 4-, and 5-substituted sites are oriented towards the narrowest part of the active site. These topological parameters are in agreement with the high auxin activity of 5, 6-Cl2-IAA and the low activity of 4, 7-Cl2-IAA.

Izvorni jezik
Engleski

Znanstvena područja
Kemija



POVEZANOST RADA


Projekti:
00980608
00981010

Ustanove:
Institut "Ruđer Bošković", Zagreb


Citiraj ovu publikaciju

Antolić, Snježana; Salopek, Branka; Kojić-Prodić, Biserka; Magnus, Volker; Cohen, Jerry D.
Structural characterization and auxin properties of dichlorinated indole-3-acetic acids // Plant growth regulation, 27 (1999), 1; 21-31 (međunarodna recenzija, članak, znanstveni)
Antolić, S., Salopek, B., Kojić-Prodić, B., Magnus, V. & Cohen, J. (1999) Structural characterization and auxin properties of dichlorinated indole-3-acetic acids. Plant growth regulation, 27 (1), 21-31.
@article{article, year = {1999}, pages = {21-31}, keywords = {dichlorinated indole-3-acetic acid, auxin, structural characterization, biological activity, Avena sativa straight growth test}, journal = {Plant growth regulation}, volume = {27}, number = {1}, issn = {0167-6903}, title = {Structural characterization and auxin properties of dichlorinated indole-3-acetic acids}, keyword = {dichlorinated indole-3-acetic acid, auxin, structural characterization, biological activity, Avena sativa straight growth test} }
@article{article, year = {1999}, pages = {21-31}, keywords = {dichlorinated indole-3-acetic acid, auxin, structural characterization, biological activity, Avena sativa straight growth test}, journal = {Plant growth regulation}, volume = {27}, number = {1}, issn = {0167-6903}, title = {Structural characterization and auxin properties of dichlorinated indole-3-acetic acids}, keyword = {dichlorinated indole-3-acetic acid, auxin, structural characterization, biological activity, Avena sativa straight growth test} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus


Uključenost u ostale bibliografske baze podataka:


  • Biological Abstracts
  • Chemical Abstracts





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