engleski

Anticipation of Patients with Schizophrenia and Course of the Disease

In this study, which was performed in Psychiatric Hospital Vrapce, Zagreb, Croatia, only those patients with schizophrenia who were admitted during 1996 for the first time in their life were included. Data were analysed according to following characteristics: gender ; age at first hospitalisation ; heredity (based on anamnestic and heteroanamnestic sources) ; type of schizophrenia and prognosis of illness. Prognosis evaluation was based on number of hospitalisations as well as on number of total inpatient days. At the end of the year 2001, after a 6-year follow-up, results showed a much better prognosis in patients with negative heredity and in those patients that were older at initial hospitalisation. Namely, in the group of patients with positive heredity the onset of the disease was statistically significant earlier ; the catatonicsubtypeofschizophreniaoccuredlessfrequentthan the simplex and hebefrenic subtypes. Those patients remain more frequent single, have less children, and less self-made income. Also, these patients spent higher persentage of time in hospital than those with negative heredity. So, theresultsof this study support the anticipation in schizophrenia.

anticipation; schizophrenia

DOI: 10.1002/ajmg.10971