engleski

Myoid cell hyperplasia in an infertile patient with azoospermia - a case report

Aim of the study. In the testis, myoid (peritubular) cells are situated within the lamina propria. These cells are thought to contract at intervals of 12-15 min. in order to "push" sperms towards the epididymis. The aim of the present study is to present a case of a male infertility with hyperplasia of myoid cells.Materials & methods. A 36- years old patient has suffered form azoospermia due to the unilateral testicular tumour. One testicle (in which the tumour was located) has been removed. An irradiation therapy was meant to follow after the unilateral orchiectomy. A biopsy of the remaining testicle was indicated in order to preserve sperms before the irradiation. Small pieces of the testicular tissue obtained by the open testicular biopsy were immediately fixed in 5.5% buffered glutaraldehyde followed by a postfixation with 1% OsO4. After dehydration, tissue was embedded in Durcopan. Semithin sections were performed by a Reichert ultramicrotome and stained with toluidine blue. Results. Testicular biopsy revealed hyperplasia of myoid cells. Instead of 5-7 layers of these cells, the lamina propria consisted of 7-14 layers of peritubular cells. Seminiferous tubules displayed a "mixed atrophy". However, in some seminiferous tubules elongated spermatids and sperms were found. Conclusion. Hyperplasia of myoid cells could be the cause of the male infertility & azoospermia.

myoid cells ; male infertility ; azoospermia

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