engleski

Pletlet count and pletlet parameters after transfuzion therapy in thrombocitosis and thrombocytopenia

Temporary increase of platlet count in whole blood determinate as thrombocitosis and decrease of them as thrombocytopenia. In both condition we have posibility for bleeding, and how difficulty is, directly dependent of platlet count. Transfuzion therapy with whole blood or platelet concetrate try correct platelet count on values adequate for physiological function. Efficiency this therapy monitoring with determined platelet count in different time after transfusions. Today, hematology systems for routin analysis of platelet, also demonstrate pletelet parametzrs like MPV, PDW and P-LCR. high variability and nonadequate investigation in many conditions eliminated this parameters to use from clinitans. Aim of this study in investigation how change platelet parameters after transfusion therapy with whole blood in burned patients with or not reactive trombocytosis (n=48) and transfusion therapy with platelet concentrate in oncology patients with thrombocytopenia (n=29. Platelet analysis in this two groups of patients we determined in three time point: previously transfusion, immediuately after and 24 hour after transfusion on hematology analysator Sysmex K-4500. This system works on impedence principe platlet counting and PDW on 20% MPV. Statistical analysis of results were done with nonparametric analyze variance from Freedman (Computer program SPSS). Statistical significance different (on level of 99.5% where is p< 0.005) we found only in platlet count in both groups. Platelet parameters show significance differences on level of 95.0% where is p<0.5 in both groups.

Pletlet; transfuzion; thrombocytopenia

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