Polymorphism of HLA class II alleles and HLA class II haplotypes in Croatian patients with psoriasis (CROSBI ID 102980)
Prilog u časopisu | kratko priopćenje
Podaci o odgovornosti
Kaštelan, Marija ; Čečuk-Jeličić, Esma ; Grubić, Zorana ; Gruber, Franjo ; Prpić, L. ; Simonić, E. ; Kaštelan, Andrija
engleski
Polymorphism of HLA class II alleles and HLA class II haplotypes in Croatian patients with psoriasis
The aim of this study was to analyse the polymorphism of HLA class II alleles and HLA class II haplotypes in type I and type II psoriasis in the Croatian population. Seventhy-seven unrelated patients with chronic stable psoriasis from the Department of Dermatology, Rijeka University Hospital Centre were classified as type I and type II psoriasis according to history data.Analysis of HLA class II alleles was performed by PCR method using SSOP. Patients with type I psoriasis (early onset, positive family history) showed significant association with DRB1*0701(RR=5.83), DQA1*0201 RR=6.12), DQB1*0201 (RR=3.29) and DQB1*0303 (7.51).
HLA class II alleles ; haplotypes ; psoriasis
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