Induction of nitric oxide in vivo or in vitro by methionine-enkephalin (CROSBI ID 463148)
Prilog sa skupa u zborniku | sažetak izlaganja sa skupa | domaća recenzija
Podaci o odgovornosti
Balog, Tihomir ; Marotti, Tanja ; Mažuran, Renata ; Ročić, Boris ; Hršak, Ivo
engleski
Induction of nitric oxide in vivo or in vitro by methionine-enkephalin
Opioid peptides are known modulators of immune functions. The aim of this study was to investigated the ability of methionin enkephalin (MENK)to induce in vivo or in vitro nitric oxide release from macrophages. We also investigated wether this effect was direct, opioid receptor mediated or indirect trough inductions of cytokines. The obtained results demonstrated that various concentration of MENK had no effect of nitric oxide release in vitro, while in vivo this effect can be stimulatory or suppressive depend of used dose. The stimulative, but not suppressive effect could be abrogated by naloxone.
Met-enkephalin; nitric oxide; macrophages
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Podaci o prilogu
15-15-x.
1997.
objavljeno
Podaci o matičnoj publikaciji
Periodicum Biologorum 99 (suppl. 2), 1997 Annual Meeting of the Croatian Immunological Society
Vitale, Branko ; Rabatić, Sabina
Zagreb: Hrvatsko prirodoslovno društvo
Podaci o skupu
Annual meeting of the Croatian Immunological Society 1997
predavanje
06.11.1997-07.11.1997
Zagreb, Hrvatska