engleski

In vitro antimicrobial susceptibility of 183 Pseudomonas aeruginosa Strains isolated from dogs to selected antipseudomonal agents

During the year 1993 through 2000, 183 strains of Pseudomonas aeruginosa were isolated from different pathological specimens originated from dogs. Antimicrobial susceptibility patterns against ten antipseudomonal agents were obtained on 183 Pseudomonas aeruginosa strains. In vitro antimicrobial susceptibility testing was performed employing the disk diffusion method (Kirby-Bauer). Antimicrobial susceptibility profiles showed that among beta-lactam antibiotic, imipenem was the most active compound. Out of 183 tested 96.7% were sensitive to imipenem. Cefoperazone showed good in vitro activity against 86.9% tested strains. Against ceftazidime strains 77.0% showed sensitivity. The less active was an old penicillin, carbenicillin with 71.6% sensitive strains. To amikacin were sensitive 87.4% isolates and 83.1% to gentamicin. Pipimedic acid, I gen. quinolone, was the less active compound of all tested, 47.0% were resistant. The in vitro sensitivity against enrofloxacin showed that 71.0% strains were sensitive and 26.2% showed resistance. Almost all tested strains 93.4% were susceptible to ciprofloxacin and marbofloxacin. Besides imipenem, the quinolone antibiotics, marbofloxacin and ciprofloxacin were the most effective against P. aeruginosa strains isolated from dogs.

Pseudomonas aeruginosa; dogs; susceptibility to antipseudomonal agents

nije evidentirano