engleski

Distraction osteogenesis by Ilizarov and unilateral external fixators in a canine model

We studied distraction osteogenesis in canine experimental model using two types of external fixators, Ilizarov (n=6) or AO unilateral (n=9) external fixator. Distraction started 1 week after surgery (2x0.5 mm/day) and lasted for 3 weeks. Specimens were harvested fromweeks 7 through 12. The outcome was assessed byX-ray, histology, histomorphology and mircoradiography. Bone regeneration as observed by X-rays was satisfactory and similar in both groups. Both endochondral ossifications and intramembranous ossification were found simultaneously in both groups. In both groups, bone formation parameters were significantly higher in the area of consolidating bone. No differences in histomorphometric parameters existed between the groups. In the study period, the bone formation was enhanced and prevailed in the distraction area. This study demonstrated the utility of the canine experimental model for the study of distraction osteogenesis.

osteogenesis; fixator; canine model

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