engleski

Analisys of circulating leptin in breast cancer patients

Leptin is an adipokine that is involved in regulation of energy balance in the body. Leptin affects different processes during growth and metastasis of solid tumors: cell proliferation, angiogenesis and tumor invasion. The interaction between leptin and cytokines in breast cancer has been shown. Furthermore, leptin signaling has been implicated in cancer chemoresistance. The aim of this study was to determine the concentration of leptin in breast cancer patients and compare it to the values ​​in healthy controls.Our results suggest higher values ​​of circulating leptin in breast cancer patients compared to healthy individuals.

breast cancer, leptin

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