engleski

Metastatic bone tumors in biopsy specimens

Metastatic bone tumors are the most common form of skeletal malignancy. The aim of the study was to present the main characteristics and the highlight the problems encountered in metastatic bone tumor biopsy. Data from the Thanatos database for the period from January 1, 1998 till December 31, 2001, were used. Pathohistological analysis was done on formalin fixed, paraffin embedded, and hamatoxylin-eosin stained tissue. Decalcification was done with nitric acid. There were 78 patients with metastatic bone tumors, 47 ( 60.3%) male and 31 (39, 7%) female. The most common site of metastases was vertebral column(74.4%). Based on the history data, pathohistologic analysis and immunohistochemical staining, the origin of metastatic tumor was identified in 73(93.6%) cases. The most common origins were cancers of the breast, kidney, lungs and prostate. The main characteristics of metastatic tumors were as expected and consistent with literature data, whereas inadequate cooperation between and pathologists was identified as the most obvious problem.

bone neoplasms diagnosis; bone neoplasms pathology; neoplasms metastasis diagnosis; secondary bone neoplasms; biopsy

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