engleski

Multisystem Inflammatory Syndrome in Children (MIS-C) associated with COVID-19

Introduction: MIS-C is increasingly common in children after recovery from COVID -19 and is associated with significant complications. The most common clinical manifestations include fever, gastrointestinal symptoms, skin rash and cardiac dysfunction. In more severe cases, cardiac decompensation or systemic organ failure occurs due to the inflammation.. Case report: An 11-year-old boy was admitted to the pulmonology department, three weeks after his second bout with COVID-19. He was admitted because of increased temperature, 39.5°C, four days ago, enlarged lymph nodes on the left side of the neck, and a maculopapular rash on the medial sides of the upper legs. Other symptoms include raspberry tongue, injected conjunctivae, and hyperemic pharynx. Initially, the symptoms suggested Kawasaki disease. Laboratory findings show an increase in inflammatory parameters with leukocytosis and an increase in urea, troponin, and IL-6. Cardiac ultrasound shows a dilated left ventricle and markedly weakened systolic function of the left ventricle, the coronary arteries are not affected and a diagnosis of myocarditis was made. Therapy consisted of IVIG 2g/kg, corticosteroids, dobutamine with furosemide, acetylsalicylic acid and antimicrobial therapy. After treatment, the systolic function of the 1st ventricle recovered completely and the patient made a full recovery. Conclusion: Since MIS-C has become very common in the pediatric population, and is often confused with Kawasaki disease, it is necessary to draw attention to therapeutic principles in the direction of symptom development (fever, lymphadenopathy, skin changes, rash, mucosal changes) and involvement of organic systems

COVID-19, children, myocarditis, a multisystem inflammatory syndrome in children (MIS-C)

nije evidentirano