Detection of bla CTX-M genes in ESBL-producing Klebsiella isolates from animals in Croatia (CROSBI ID 328327)
Prilog u časopisu | ostalo | međunarodna recenzija
Podaci o odgovornosti
Pintarić, Selma ; Štritof, Zrinka ; Mojčec Perko, Vesna ; Tumpa, Andrea ; Cvetnić, Marija ; Hadžić, Lana
engleski
Detection of bla CTX-M genes in ESBL-producing Klebsiella isolates from animals in Croatia
This study investigated the frequency of third- generation cephalosporin resistance in Klebsiella spp. isolated from animals in Croatia and the presence of blaCTX-M genes. A total of 711 enteric bacteria were isolated from clinical samples, and Klebsiella spp. isolates accounted for 6.9% (n = 49). Thirteen Klebsiella isolates (26.5%) were ESBL producers, nine isolates from the Klebsiella pneumoniae species complex (69.2%), and four (30.8%) Klebsiella oxytoca isolates. All carried the blaCTX-M-15 gene, and antimicrobial susceptibility testing revealed them as multidrug resistant. All were resistant to all tested cephalosporins, fluoroquinolones, aminoglycosides and aztreonam, 92.3% showed resistance to tetracycline, 84.6% to trimethoprim- sulfamethoxazole and 69.2% to nitrofurantoin. No isolate showed resistance to imipenem and meropenem. It can be concluded that ESBL-producing Klebsiella expressing the blaCTX-M gene are not rare among Klebsiella isolates from animals in Croatia.
Klebsiella spp., ESBL, blaCTX-M, animals, multidrug resistance
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Podaci o izdanju
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2023.
rani pristup (online first)
0236-6290
1588-2705
10.1556/004.2023.00845