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Synthesis and cis-trans isomerism in novel Leu-enkephalin-related peptidomimetics containing N-glycated glycine residues


Čudić, Mare; Horvat, Jaroslav; Elofsson, Mikael; Bergquist, Karl-Erik; Kihlberg, Jan; Horvat, Štefica
Synthesis and cis-trans isomerism in novel Leu-enkephalin-related peptidomimetics containing N-glycated glycine residues // Journal of the Chemical Society. Perkin transactions. I, 11 (1998), 1789-1795 doi:10.1039/A801472H (međunarodna recenzija, članak, znanstveni)


Naslov
Synthesis and cis-trans isomerism in novel Leu-enkephalin-related peptidomimetics containing N-glycated glycine residues

Autori
Čudić, Mare ; Horvat, Jaroslav ; Elofsson, Mikael ; Bergquist, Karl-Erik ; Kihlberg, Jan ; Horvat, Štefica

Izvornik
Journal of the Chemical Society. Perkin transactions. I (0300-922X) 11 (1998); 1789-1795

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Cis/trans ; isomerism ; opioid ; peptidomimetic ; glycation

Sažetak
The influence of a new peptoid residue on amide bond stereochemistry has been explored via the synthesis and NMR analysis of novel peptidomimetics related to the endogenous opioid pentapeptide Leu-enkephalin. The compounds studied include enkephalin analogues N-alkylated at either the second or both the second and the third amino acid residues with 6-deoxy-D-galactose moiety.

Izvorni jezik
Engleski

Znanstvena područja
Kemija



POVEZANOST RADA


Projekt / tema
00980704

Ustanove
Institut "Ruđer Bošković", Zagreb

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus


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