The Croatian Primary Sjögren's Syndrome Oral Health Study: Oral Status and Oral Health-Related Quality of Life (CROSBI ID 734612)
Prilog sa skupa u zborniku | sažetak izlaganja sa skupa | međunarodna recenzija
Podaci o odgovornosti
Glavina, Ana ; Božić, Ivona ; Parat, Katica ; Perković, Dijana ; Martinović Kaliterna, Dušanka ; Biočina Lukenda, Dolores ; Radić, Mislav
engleski
The Croatian Primary Sjögren's Syndrome Oral Health Study: Oral Status and Oral Health-Related Quality of Life
Background and Aims: To determine salivary flow rate, oral and periodontal status, OHRQoL, objective (ESSDAI) and subjective (ESSPRI, 6- items-VAS-SS, Profile of Fatigue) indexes, and serum antibody reactivity in patients with primary Sjögren's Disease (pSD). Methods: Thirty-one patients with pSD and 31 control subjects participated in this cross- sectional, single-center study. The unstimulated whole salivary flow rate (UWSFR) and stimulated whole salivary flow rate (SWSFR), salivary pH, DMFT index, periodontal pocket depth (PPD), clinical attachment level (CAL), interincisal distance, OHRQoL, objective (ESSDAI) and subjective (ESSPRI, 6-items-VAS-SS, Profile of Fatigue) indexes were analyzed. Biochemical analysis of serum from a blood sample was performed. Results: The mean DMFT index of pSD patients was 23.74 ± 7.28 compared with control subjects (20.77 ± 5.73), without statistical significance (p=0.08, T-test). The prevalence of periodontitis was the same in pSD patients and control subjects (83.87% vs. 77.42%), without statistical significance (p=0.348, λ2 test). ESSDAI correlated positively with UWSFR (p <0.001, r = 0.708, Spearman's rank coefficient), SWSFR (p <0.001, r = 0.743), and total OHIP-49 score (p <0.001, r = 0.949). There was no association between periodontitis and the observed autoantibodies (anti-Ro/SSA, anti-La/SSB, anti-TRIM21, RNP) (p=0.631, p=0.530, p=0.469, and p=0.640, respectively ; Fisher's exact test). Conclusions: Primary SD patients have decreased salivary flow and salivary pH, poor oral health, decreased interincisal distance, high prevalence of periodontitis, and worse OHRQoL. The strong and statistically significant association of the objective parameter of the pSD (ESSDAI) with parameters of the oral cavity (UWSFR, SWSFR) shows that oral status is significantly related to the severity of the underlying disease.
Sjögren's Disease ; ESSDAI ; ESSPRI ; periodontal diseases ; oral health
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Podaci o prilogu
117-117.
2023.
objavljeno
Podaci o matičnoj publikaciji
Torino:
Podaci o skupu
7th International Congress on Controversies in Rheumatology & Autoimmunity
poster
16.03.2023-18.03.2023
Torino, Italija