The signature of inverse hexagonal phase of phosphoethanolamine lipids (CROSBI ID 734509)
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Podaci o odgovornosti
Maleš, Petra ; Bakarić, Danijela
engleski
The signature of inverse hexagonal phase of phosphoethanolamine lipids
The compositional variations of lipids in the myelin sheath are responsible for nerve conduction failure and neurodegeneration that may ultimately result in demyelinating diseases such as multiple sclerosis (MS). A significant enhancement of phosphoethanolamine (PE) lipids in myelin at pathological conditions is presumably associated with a greater probability that PE lipids, besides forming lamellar (L/L) structures, can be arranged in nonlamellar inverse hexagonal phase (HII) that structurally resembles to the vacuoles, similar to those caused by demyelination. When 1- palmitoyl-2-oleoyl-sn-glycero-3- phosphoethanolamine (POPE), as one of the most common lipids in myelin membrane, is suspended in water, along with L/L phases POPE can also form HII, distinguished by inverted lipid cylinders with the polar headgroups of lipids facing the water surroundings.
Phosphoethanolamine ; Liposomes
nije evidentirano
nije evidentirano
nije evidentirano
nije evidentirano
nije evidentirano
nije evidentirano
Podaci o prilogu
98-98.
2023.
objavljeno
Podaci o matičnoj publikaciji
28HSKIKI : 28th Croatian Meeting of Chemists and Chemical Engineers and 6th Symposium Vladimir Prelog : Book of Abstracts
Rogošić, Marko
Zagreb: Hrvatsko društvo kemijskih inženjera i tehnologa (HDKI)
2757-0754
Podaci o skupu
28.Croatian Meeting of Chemists and Chemical Engineers and 6th Symposium Vladimir Prelog
poster
28.03.2023-31.03.2023
Rovinj, Hrvatska