engleski

Antibiotics consumption in Republic of Croatia during the five year period

INTRODUCTION: The aim of this research was to investigate consumption of most prescribed antibiotics in public health system's dental offices from 2015. to 2020. in Croatia. MATERIALS AND METHODS: This retrospective study collected data from all public health system's dental offices in Croatia. 1.535.139 data were collected from the Central Information Health System of Croatia (CEZIH) in the period of five years. Sample contained data about types of prescribed anitbiotics, number of antibiotics' prescription, number of prescribers and geological locations of dental practices. The consumption of antiobiotics is expressed in Defined Daily Dose per 1000 inhabitants per day (DID), which is calculated using this formula: Utilization in DDDs x 1000/ No. of inhabitans x No. of days in the period of data collections. RESULTS: In 2015. DID for amoxicillin with clavulanic acid was 1.4 and in 2019. 2.0, in 2015. DID for amoxicillin was 0.3 and in 2019. 0.4 DID, in 2015. DID for Clindamycine was0.1 and in 2019. 0.1, in 2015. DID for metronidazole was 0.1 and in 2019. 0.1. The highest increase in five year time period (119%) was for metronidazole. CONCLUSION: In the observed period the most prescribed antibiotic was Amoxicillin with clavulanic acid followed by Amoxicillin, Clindamycin, and Metronidazole. with significant increased consumption in 2019 for all of antibiotics, but especially metronidazole

Antibiotics consumption, Defined Daily Dos

nije evidentirano