In-vivo results of NOVAMag® fixation screw XS performance study (CROSBI ID 734037)
Prilog sa skupa u zborniku | sažetak izlaganja sa skupa | međunarodna recenzija
Podaci o odgovornosti
Rider, Patrick ; Perić Kačarević, Željka ; Elad, Akiva ; Rothamel, David ; Sauer, Gerrit ; Bornert Fabien ; Windisch, Peter ; Hangyási, Dávid ; Molnar, Balint ; Hesse, Berhard ; Assad, Michael ; Witte, Frank ; Rogge, Svenja ; Tadić, Dražen
engleski
In-vivo results of NOVAMag® fixation screw XS performance study
INTRODUCTION: The most commonly used fixation systems in dentistry are non-resorbable titanium screws. Alternative resorbable magnesium WZM211 alloy screws with a MgF2 surface are presented and compared to standard titanium screws for membrane fixation in a guided bone regeneration model in beagle dogs, data previously published. Examples of the magnesium screw’s application to clinical cases will also be shown. METHODS: Twenty Beagle dogs had four 3-wall defect sites treated in the mandible (2 sites on the left and 2 on the right). Defects were filled with bovine bone granules, covered with a collagen membrane and secured with either 4 magnesium screws or 4 titanium screws. Animal wellbeing was regularly checked by a veterinary team. Cohorts of six animals were assigned to 1 week, 8 week and 16 week timepoints, with 2 spare animals that were later assigned to a 52 week timepoint. Micro-CT and histological evaluation were performed for defect analysis at each timepoint. DISCUSSION & CONCLUSIONS: The expected observations of transient inflammation and pain were observed postoperatively. A good healing response was demonstrated in both groups. Micro-CT analysis showed no significant difference between groups in terms of relative bone volume or soft tissue volume. Initially void space was observed in the magnesium screw group caused by the release of hydrogen gas, however, the void volume continued to decrease on average between each timepoint. Volumetric measurement of the magnesium screws showed a gradual progression of the degradation process until no remnants were visible at the 52 week timepoint. Overall, the magnesium screws and titanium screws showed equal performance in tissue regeneration according to the principles of guided bone regeneration. Yet the magnesium screws had the additional advantage of being completely resorbable. The success of the in-vivo performance study has since been replicated in a clinical setting.
NOVAMag® screw ; biodegradable ; magnesium metal
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Podaci o prilogu
1
2022.
objavljeno
Podaci o matičnoj publikaciji
14 th Metal Symposium on Biodegradable Metals for Biomedical Application
Mantovani, D ; Witte, F ; Zheng, Y ; Staiger, M
Alicante: video5@ulaval.ca
Podaci o skupu
Symposium on Biodegradable Metals for Biomedical Application
predavanje
24.08.2022-29.08.2022
Alicante, Španjolska