engleski

Update of resorbable metal in dentistry: the NOVAMag® regeneration system

The NOVAMag® regeneration system has been the first system made of biodegradable magnesium metal that has received CE approval in the dental field. It is a system specifically designed for regenerative procedures in the alveolar jaw, such as GBR and bone block fixation. Guided bone regeneration is a well-established technique that requires the use of a barrier membrane that can be secured in place using devices such as pins or screws to secure bone granules in the augmented area. The membrane and its fixation system can be made from either resorbable or non-resorbable materials, however each choice of material has its own advantages and disadvantages. Non-resorbable membranes provide the advantage of maintaining their shape and structure for the duration of the treatment yet require a second surgical procedure for their removal. Resorbable membranes can have problems related to their degradative by-products as well as their lack of rigidity and stability. Non-resorbable fixation screws provide a secure fixation of barrier membranes or bone blocks, however, have an unacceptable level of palpability, intraoral exposure, passive migration, particle release as well as distortion of magnetic resonance in diagnostic images. Resorbable polymeric fixation screws have reported issues such as their breakage and the induction of inflammatory or delayed foreign body reactions. Due to the reported complications of both the resorbable and non-resorbable devices, alternative technologies have been explored. Magnesium is a biodegradable metal that is mechanically strong and durable, and is completely resorbed by the human body without toxic residuals, thereby encompassing the benefits of both the resorbable and non-resorbable materials. Magnesium has already been successfully applied in orthopaedic and cardiovascular applications, but only recently clinically applied in regenerative dentistry. Over the course of the lecture, the NOVAMag® regeneration system and its clinical application will be presented. Key aspects of medical device requirements are covered, including material properties and how these translate into a usable medical device that can be successfully used in the clinic. Recommendations for the introduction onto the market of new resorbable biometal medical devices are also presented.

NOVAMag® ; biodegradable ; magnesium metal

nije evidentirano