engleski

Food frequency questionnaire analysis in patients with Hashimoto's thyroiditis

Genetic and environmental factors play a role in development of Hashimoto’s thyroiditis (HT). As food intake is considered to be an important environmental factor, we aimed to evaluate food habits of HT patients, measured by self-reported food frequency questionnaire (FFQ). FFQ, composed of 51 food-items, was collected from 491 HT cases and 433 controls originating from the region of Split. Prior analysis, we grouped food items into 22 food groups and calculated weekly intake of each food group per individual. We analysed differences in weekly intake of 22 food groups between HT cases and controls to identify specific foods that are consumed more or less frequently in HT cases than in controls. Food groups that are more frequently consumed in HT patients were animal fat, processed meat and nuts whereas whole grains, caloric drinks, red meat, plant oil, olive oil, hard liquor, blue fish and fruits were less frequently consumed. Animal fat has already been associated with high thyroid peroxidase antibodies that are key markers of HT. We have narrowed down the list of potential food factors that may play a role in HT status. Our results are observational and need to be confirmed in interventional trail.

Hashimoto's thyroiditis, food questionnaire, diet

nije evidentirano