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Depression and Quality of life in Patients with Epilepsy – Single Centre Experience (CROSBI ID 733284)

Prilog sa skupa u časopisu | sažetak izlaganja sa skupa | međunarodna recenzija

Petelin Gadže, Željka ; Tudor, Katarina Ivana ; Živković, Maja ; Bujan Kovač, Andreja ; Đapić Ivančić, Biljana ; Nanković, Sibila ; Šulentić, Vlatko ; Brezak, Ira ; Nimac Kozina, Petra ; Sitaš, Barbara et al. Depression and Quality of life in Patients with Epilepsy – Single Centre Experience // Liječnički vjesnik : glasilo Hrvatskog liječničkog zbora. Suplement. 2020. str. 59-60 doi: 10.26800/LV-142-Suppl1-2

Podaci o odgovornosti

Petelin Gadže, Željka ; Tudor, Katarina Ivana ; Živković, Maja ; Bujan Kovač, Andreja ; Đapić Ivančić, Biljana ; Nanković, Sibila ; Šulentić, Vlatko ; Brezak, Ira ; Nimac Kozina, Petra ; Sitaš, Barbara ; Radić, Borislav ; Mudrovčić, Monika ; Poljaković, Zdravka ; Hajnšek, Sanja

engleski

Depression and Quality of life in Patients with Epilepsy – Single Centre Experience

Introduction and objectives. Epilepsy is often associated with comorbid psychiatric illnesses and the most frequent of these, in around 40% of patients, is major depressive disorder. Compared to general population epidemiological studies show a consistent increased prevalence of depression in epilepsy. The main aim of this study was to evaluate the relationship between epilepsy, antiepileptic drugs (AEDs) and depression. We also wanted to evaluate possible association between depressive symptoms in patients with epilepsy with the quality of life (QoL). Methods. This was a prospective cross-sectional study carried out at the tertiary teaching hospital (University Hospital Centre Zagreb, Croatia) with Ethics committee approval. Questionnaires evaluating depressive symptoms and QoL were administered to consecutive patients treated in the Referral Centre of the Ministry of Health of the Republic of Croatia for Epilepsy. Depressive symptoms were evaluated using Hamilton Rating Scale for Depression (HAM- D17). Quality of life was assessed using Quality of life in epilepsy-31 inventory (QOLIE-31). Statistical analysis was done using statistical software IBM Corp. Released 2011. IBM SPSS Statistics for Windows, Version 20.0. Armonk, NY: IBM Corp, using t-test, one way ANOVA, post hoc Scheffe test, Bonferroni, Tukey test, and Pearson correlation coefficient. Results. 108 patients (63% women, 37% men ; mean age 39.54 ± 15.91 years) with epilepsy were included. 14.8% of patients had focal, 35.2% generalised and 40.7% both types of epilepsy. Majority of patients (65.74%) were on two and more AEDs and quarter was on monotherapy (25%) ; 42% were on newer, 19% on older and 39% on both AEDs. Mean total score on HAM- D17 was 9.94 ± 8.18 (men – mean total score 10.16 ± 8.85, women – mean total score 9.81 ±7.84). There were no significant differences on HAM- D17 regarding gender and age. We didn’t find statistically significant differences regarding AEDs (older vs. newer AEDs, or both types AEDs) and results on HAM- D17, nor between the type of epilepsy and results on HAM – D17. We found strong negative correlation between the higher QoL and HAM – D17 (p=0.000). Conclusions. Results of this study evaluating depressive symptoms in patients with epilepsy demonstrate that our patients mainly experience mild depressive symptoms, with no significant differences on HAM- D17 regarding gender and age. Patients with epilepsy with less pronounced depressive symptoms were found to have higher QoL. We did not find statistically significant differences regarding the type of epilepsy and results on HAM – D17, nor between the AEDs (older vs. newer AEDs, or both types AEDs) and results on HAM- D17.

epilepsy ; quality of life

nije evidentirano

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Podaci o prilogu

59-60.

2020.

nije evidentirano

objavljeno

10.26800/LV-142-Suppl1-2

Podaci o matičnoj publikaciji

Liječnički vjesnik : glasilo Hrvatskog liječničkog zbora. Suplement

1330-4917

Podaci o skupu

Better Future of Healthy Ageing 2020

poster

03.06.2020-05.06.2020

online ; Zagreb, Hrvatska

Povezanost rada

Kliničke medicinske znanosti

Poveznice