Clinical characteristics and treatment outcome of patients with sepsis treated in an infectious disease intensive care unit (CROSBI ID 733103)
Prilog sa skupa u zborniku | sažetak izlaganja sa skupa | međunarodna recenzija
Podaci o odgovornosti
Novak, Rafaela ; Popović, Marta ; Baršić, Bruno ; Santini, Marija ; Kutleša, Marko ; Krajinović, Vladimir
engleski
Clinical characteristics and treatment outcome of patients with sepsis treated in an infectious disease intensive care unit
Background: In most countries of the European Union patients suffering from sepsis are commonly treated in general intensive care units (ICU). By contrast, in some European countries, as well as in Zagreb, Croatia, these patients are admitted to a specialized infectious disease intensive care unit (IDICU). The study aimed to evaluate the clinical and epidemiological features of patients with severe sepsis admitted to an IDICU and compare treatment outcome in IDICU with literature data on the outcome of patients admitted to a non- IDICU. Materials/methods: This research is a retrospective data analysis on 408 patients with the diagnosis of sepsis admitted to the 18-bed IDICU of the University Hospital for Infectious Diseases in Zagreb, Croatia over a three year period (January 2016 to December 2018). Results: The admitting diagnosis of sepsis represented 35% of all admitting diagnoses in the IDICU. Nearly 2/3 of admitted patients with sepsis were men and the age median was 65 (IQR 55-75), whereas the median of Charlson Comorbidity Index (CCI) was 3 (IQR 2-5). Septic shock was present in 40% of patients, while the median of Sequential Organ Failure Assessment Score (SOFA) was 7 (IQR 4-11). In the IDICU the median patient length of stay was 8 (IQR 3-19) days. The most commonly associated infections were neurological (16%), endocarditis (15%) and urinary tract infections (12%). The specific mortality rate among patients with sepsis was 14%. Around 10% of admitted patients with sepsis were discharged from the IDICU as independent and mobile, while 23% of patients were left with reduced functional disability and 27% of patients were completely dependent and immobile, with case fatality rate of 40%. Conclusions: The proportion of admitted patients with sepsis in the IDICU was 35%, which is higher than in other ICU-s in Croatia (10-20%) according to literature. The specific mortality rate of IDICU patients of 14% was though in the lower portion of the compared specific mortality range for sepsis (10-50%). Taken into consideration that the admitted patients had higher CCI and SOFA scores, we observed that the type of ICU may have had an impact on the treatment outcome.
Clinical characteristics ; treatment ; sepsis ; treatment ; intensive care unit
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Podaci o prilogu
4014-4014.
2020.
objavljeno
Podaci o matičnoj publikaciji
Podaci o skupu
30th ECCMID 2020
poster
18.04.2020-21.04.2020
Pariz, Francuska