Does the type of surgery in brain abscess patients influence the outcome? Analysis based on the propensity score method (CROSBI ID 322202)
Prilog u časopisu | izvorni znanstveni rad | međunarodna recenzija
Podaci o odgovornosti
Penezić, Ana ; Santini, Marija ; Heinrich, Zdravko ; Chudy, Darko ; Miklić, Pavle ; Baršić, Bruno
engleski
Does the type of surgery in brain abscess patients influence the outcome? Analysis based on the propensity score method
There are different options for surgical treatment of brain abscess, mainly standard craniotomy and stereotactic aspiration. It has not yet been established which of these options is associated with a more favorable outcome under similar baseline conditions of patients. Demographic char- acteristics, microbiology, clinical presentation, and treatment outcome were analyzed for surgically treated adult patients with brain abscess over a 14-year period. A propensity score model was applied to account for baseline conditions that may determine the choice of neurosurgical method. The propensity score was included in the prediction of a favorable outcome, defined as a Glasgow Outcome Scale (GOS) score 4 or 5. We analyzed 91 adult surgically treated patients, of which 53 had standard craniotomy and 38 stereotactic aspiration of brain abscess. Focal neurological deficit was the most common symptom present in 60 (65.9%) patients on admission. Sixty-seven (73.6%) patients had GOS 4 or 5, and seven (7.7%) patients died. The choice of surgery did not influence the outcome (OR 1.181, 95% CI 0.349-3.995), neither did the time elapsed from diagnosis to surgery (OR 0.998, 95% CI 0.981- 1.015). Propensity towards standard craniotomy procedure did not influence outcome in brain abscess patients (OR 1.181, 95% CI 0.349-3.995). Worse outcome (GOS below 4) was inde-pendently associated with Glasgow Coma Score (GCS) on admission (OR 0.787, CI 0.656-0.944). The choice of neurosurgical procedure did not influence the outcome in patients with brain abscess. Patients with brain abscess who had lower GCS on admission also had worse outcome.
brain abscess ; craniotomy ; Glasgow outcome scal ; stereotactic aspiration
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Podaci o izdanju
60 (4)
2021.
559-568
objavljeno
0353-9466
1333-9451
10.20471/acc.2021.60.04.01
Povezanost rada
Kliničke medicinske znanosti