engleski

Reevaluation by biological standardization of known allergenic potency of a Dactylis glomerata extract.

Standardized and liophylised Dactylis glomerata pollen extract with concentration of 10000, 1000 and 100 BU/ml was evaluated by the skin prick test method in the skin of allergic individuals previously did not receive allergen-specific immunotherapy.Histamine skin reaction was equal to 10000 BU/ml done at the ulnar side of the forearm.But on the radial side it was significantly smaler (p<0, 001). That was lower than the allergen potency declared by manufacturer.In this group of patients 1000BU/ml was equivalent to histamine 1 mg/ml.The importance of this study was in the fact that biologicaly standardized allergen extract was evaluated in our country.

biological standardization, allergenic potency

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