engleski

Primary synchronous uveal and skin malignant melanoma : case report

Simultaneous occurrence of primary uveal melanoma and skin melanoma is rare. We presented a 66 year old female patient with primary synchronous choroidal and skin malignant melanoma on right upper-arm. The patient has a negative family history for cutaneous or uveal melanomas and did not display the dysplastic nevus syndrome phenotype. Six years after enucleation of left bulbous and skin excision of malignant melanoma the patient presented with lymphatic metastasis in right axillary lymph nodes. After two years metastases in mesenteric lymph nodes and solitary nodule in spleen appeared. Nine years after initial presentation of melanomas patient developed metastases in ingvinal lymph node. Metastatic spread was most probably due to lymphatic dissemination of more biologically aggressive primary skin malignant melanoma. Ten years after initial diagnoses the patient is alive and without new metastases.

uveal melanoma; primary cutaneous malignant melanoma; simultaneous occurrence; risk factors

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