engleski

Botulin toxin A in lower lid entropium correction

INTRODUCTION/OBJECTIVES: to evaluate the clinical results and report the results of 12 cases of senile involutional entropion of the lower lid treated with botulinum toxin MATERIALS AND METHODS: Twelve patients with senile entropion were treated with an injection of botulinum toxin. The mean age was 67, 2±7, 3. The toxin (Botox ; Allergan Corporation, Irvine, CA) was supplied in a vial contained 100 units of freeze-dried botulinum toxin A. This was reconstituted and diluted with 2 ml of saline which resulted with a concentration of five units in 0.1. The reconstituted toxin was injected over the orbicularis oculi muscle subcutaneously 4 mm below the eyelash margin of lower eyelid at three sites with a 30-gauge needle. Five units of the toxin were injected in each site (15 units total). The patients were examined 7 days after the aplication, 30 days and then monthly up to 1 year. RESULTS: In all treated patients improvement of the eyelid margin was visible within three to four days after the injection with the duration which varied from 8 to 16 weeks. No complications or side effects of the treatment was recorded. CONCLUSION: Botulinum toxin A can be effective temporary treatment for senile lower lid entropion.

botulinum toxin, senile entropion, treatment

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