INFLUENCE OF GENETIC SUB-STRUCTURING OF STATISTICAL FORENSIC PARAMETERS ON GENETIC STR MARKERS IN THE POPULATIONS OF SOUTHEASTERN EUROPE (CROSBI ID 732135)
Prilog sa skupa u zborniku | sažetak izlaganja sa skupa | domaća recenzija
Podaci o odgovornosti
Novokmet, Natalija ; Peričić Salihović, Marijana ; Škaro, Vedrana ; Projić, Petar ; Šarac, Jelena ; Havaš Auguštin, Dubravka ; Missoni, Saša ; Rudan, Pavao ; Primorac, Dragan ; Marjanović, Damir
engleski
INFLUENCE OF GENETIC SUB-STRUCTURING OF STATISTICAL FORENSIC PARAMETERS ON GENETIC STR MARKERS IN THE POPULATIONS OF SOUTHEASTERN EUROPE
The goal was to perform a meta-analysis of synthesized data and investigate the influence of specific intrapopulation genetic structures on interpopulation relationships. Special focus was the influence of island population isolation on the substructuring of the Croatian population, and the influence of regional population groups on the substructuring of Southeast Europe. A long-term goal is to develop a model of appropriate sampling of the total population when creating a database of genetic STR markers that would properly reflect all the characteristics of included subpopulations. Autosomal STR loci were analyzed using four forensic parameters (match probability, power of discrimination, power of exclusion and the degree of polymorphism) on a sample of 2877 unrelated participants of both sexes. The analysis was performed using the statistical package PowerStats v1.2. The comparison of forensic parameters between different subpopulations of Croatia and Southeast Europe indicates that the isolation of individual Croatian subpopulations and certain rare alleles in their gene pool affect the values of forensic parameters. Specific features of (sub)populations should be taken into account for appropriate sampling of the total population when creating a DNA database of STR markers.
STRs ; genetic sub-structuring ; forensic parameters ; Croatia ; Southeast Europe
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Podaci o prilogu
2022.
objavljeno
Podaci o matičnoj publikaciji
8. Hrvatskom kongresu humane genetike / 1. Hrvatskom kongresu personalizirane medicine
Podaci o skupu
8. Hrvatskom kongresu humane genetike / 1. Hrvatskom kongresu personalizirane medicine
predavanje
20.06.2022-20.06.2022
Dubrovnik, Hrvatska