engleski

RELATIONSHIP OF BODY COMPOSITION WITH OSTEOPOROSIS

Osteoporosis is a skeletal disease characterized by low bone mass and microarchitectural deterioration of bone tissue with a consequent increase in bone fragility and susceptibility to fracture. Osteoporosis was defined by the World Health Organization (WHO) in 1994 as a bone mineral density of less than 2.5 standard deviations below the sex-specific young adult mean and this characterization has been adopted globally. The term sarcopenia was first coined in 1989 by Irwin Rosenberg who used it to define/describe the loss of muscle mass with age and it is associated with increased rates of disability, poor mobility, frailty and hospitalization. Since then it has been known that muscle function, in addition to muscle mass, is necessary to describe sarcopenia. Osteoporosis and sarcopenia are common diseases in older age and are associated with significant morbidity and mortality. They represent two major health problems with an increasing prevalence in the elderly population. The correlation be-tween these diseases has been widely reported, leading to the development of the term “osteosarcopenia” which is used to diagnose those patients suffering from both dis-eases. A universal definition was established for osteoporosis in 1994. but for sarcopenia there is still ongoing debate regarding how best to define it. Human body composition measurements are objective methods of nutritional assessment and area of interest to health professionals. Despite many clinical trials and epidemiological studies, we still didn’t define how changes in hu-man body composition affect clinical and functional status in both patients with osteoporosis and sarcopenia. Reasons for that are often found in poorly available diagnostic methods and low motivation of health professionals in relationship of body composition and osteoporosis. CT and MRI represent the gold standard for evaluating body composition (BC), but are costly and time-consuming. Bioelectrical impedance analysis (BIA)is emerging as a popular alternative to DXA due to its easy installation and superior cost-effectiveness. BIA measures tissue impedance by circulating a weak alternating current through the body. Using BIA, we tried to define the relationship of body com- position in patients with osteoporosis during the pilot study in cohort of Croatian patients with osteoporosis.

OSTEOPOROSIS ; BODY COMPOSITION

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