Feasibility of obinutuzumab (G) combined with higher doses of chlorambucil (Clb) for frontline treatment of CLL: a retrospective non-interventional study of KroHem, the Croatian Cooperative Group for Hematologic Diseases (CROSBI ID 731696)
Prilog sa skupa u časopisu | prošireni sažetak izlaganja sa skupa | međunarodna recenzija
Podaci o odgovornosti
Aurer, Igor ; Jakšić, Ozren ; Basic-Kinda, Sandra ; Mišura Jakobac, Karla ; Sinčić-Petričević, Jasminka ; Novaković Coha, Sabina ; Galušić, Davor ; Holik, Hrvoje ; Valković, Toni ; Županić-Krmek, Dubravka ; Dragicevic, Ida Hude ; Milunović, Vibor ; Pejša, Vlatko
engleski
Feasibility of obinutuzumab (G) combined with higher doses of chlorambucil (Clb) for frontline treatment of CLL: a retrospective non-interventional study of KroHem, the Croatian Cooperative Group for Hematologic Diseases
Prolonged steroid premedication and/or reduction of lymphocyte count with Clb prior to administering first dose of G might result in a lower frequency of severe infusion reactions observed in our series In contrast to rituximab, the combination of G with higher-doses of Clb frequently results in premature stopping of the latter, especially in patients with serious comorbidities. This prevents the delivery of the intended total dose of Clb and reduces the possibility to improve efficacy over G þ Clb pulses.
KroHem ; obinutuzumab (G) ; chlorambucil (Clb)
nije evidentirano
nije evidentirano
nije evidentirano
nije evidentirano
nije evidentirano
nije evidentirano
Podaci o prilogu
111-112.
2020.
nije evidentirano
objavljeno
10.1080/10428194.2020.1732667
Podaci o matičnoj publikaciji
Leukemia & lymphoma
1042-8194
1029-2403
Podaci o skupu
Nepoznat skup
poster
29.02.1904-29.02.2096
Povezanost rada
Kliničke medicinske znanosti