Selection, validation, and utilization of mitogenome SNP array information in cattle breeding (CROSBI ID 731688)
Prilog sa skupa u zborniku | izvorni znanstveni rad | međunarodna recenzija
Podaci o odgovornosti
Brajkovic, Vladimir ; Bradic, Leona ; Turkalj, Katarina ; Novosel, Dinko ; Ristov, Strahil ; Ajmone-Marsan, Paolo ; Colli, Licia ; Cubric- Curik, Vlatka ; Solkner, Johann ; Curik, Ino
engleski
Selection, validation, and utilization of mitogenome SNP array information in cattle breeding
High-density SNP arrays are routinely used for genetic improvement of livestock populations. At the same time, mitogenome SNPs have rarely been used. In this study, we empirically evaluated 331 mitogenome SNPs included in the GGP Bovine 100K SNP array developed in collaboration with NEOGEN Genomics (Lincoln, NE, USA). Here we present a pipeline for the potential use of mitogenome SNPs with some examples: i) classification of haplogroups with emphasis on rare ones (I, P, Q, R and T5), ii) pedigree verification iii) pedigree and haplotype imputation, iiii) deleterious mutation detection iv) mitogenome and nuclear diversity, and v) standard mitogenome classification and phylogenetics. In summary, 317 mitogenome SNPs have been successfully validated and contribute as additional information to autosomal markers in population genomic analyses. We believe that our study will help to promote the use of mitogenome information in cattle breeding and biodiversity management.
Mitogenome ; SNPs ; Selection ; Validation ; Utilization
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Podaci o prilogu
2826-2829.
2022.
objavljeno
10.3920/978-90-8686-940-4_685
Podaci o matičnoj publikaciji
Proceedings of 12th World Congress on Genetics Applied to Livestock Production (WCGALP)
Podaci o skupu
12th World Congress on Genetics Applied to Livestock Production (WCGALP)
predavanje
03.07.2022-07.07.2022
Rotterdam, Nizozemska
Povezanost rada
Biologija, Interdisciplinarne biotehničke znanosti, Poljoprivreda (agronomija)