Impact of NH4+ and Gdm+ cations on thermal properties of DPPS lipid membranes (CROSBI ID 730480)
Prilog sa skupa u zborniku | sažetak izlaganja sa skupa | domaća recenzija
Podaci o odgovornosti
Pašalić, Lea ; Bakarić, Danijela
engleski
Impact of NH4+ and Gdm+ cations on thermal properties of DPPS lipid membranes
Phospholipid molecules present an essential part of biomembranes. Phosphatidylserine (PS) is the major anionic phospholipid present in eukaryotic membranes located on the cytosolic leaflet. One of its primary functions seems to be to impart a negative charge to the inner surface of the membrane lipid bilayer [1] which is required for the binding and activation of various peripheral membrane proteins [2]. Lipid-constitued membranes undergo phase transitions, which in addition to temperature, pressure, and pH also depend on the chemical potentials of ions [3]. In this work we are focused on monitoring thermal properties of lipid membranes constituted from 1, 2-dipalmitoyl- snglycero-3-phosphatidylserine (DPPS) in the presence of guanidinium (Gdm+ ) and ammonium (NH4 + ) cations which is manifested in a change in melting temperature (Tm). Using FT-IR spectroscopy, UV-Vis spectrophotometry, and differential scanning calorimetry (DSC) our goal is to understand how thesecations affects thermal properties of DPPS lipid membranes. All experimental results are supported by the computational study.
Biomembranes ; phospholipids ; spectroscopy ; calorimetry
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Podaci o prilogu
148-149.
2022.
objavljeno
Podaci o matičnoj publikaciji
6. simpozij studenata doktorskih studija PMF-a : knjiga sažetaka = 6th Faculty of Science PhD student symposium : book of abstracts
Schneider, Petra
Zagreb: Prirodoslovno-matematički fakultet Sveučilišta u Zagrebu
978-953-6076-93-2
Podaci o skupu
6. Simpozij studenata doktorskih studija PMF-a = 6th Faculty of Science PhD Student Symposium
poster
23.05.2022-24.05.2022
Zagreb, Hrvatska