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izvor podataka: crosbi

Depression and quality of life in patients with epilepsy - single centre experience (CROSBI ID 730275)

Prilog sa skupa u časopisu | kratko priopćenje | međunarodna recenzija

Petelin Gadže, Željka ; Tudor, Ivana Katarina ; Živković, Maja ; Bujan Kovač, Andreja ; Đapić Ivančić, Biljana ; Nanković, Sibila ; Šulentić, Vlatko ; Brezak, Ira ; Nimac Kozina, Petra ; Sitaš, Barbara et al. Depression and quality of life in patients with epilepsy - single centre experience // Psychiatria Danubina. 2021. str. 486-489

Podaci o odgovornosti

Petelin Gadže, Željka ; Tudor, Ivana Katarina ; Živković, Maja ; Bujan Kovač, Andreja ; Đapić Ivančić, Biljana ; Nanković, Sibila ; Šulentić, Vlatko ; Brezak, Ira ; Nimac Kozina, Petra ; Sitaš, Barbara ; Radić, Borislav ; Mudrovčić, Monika ; Mijatović, Dragana ; Poljaković, Zdravka ; Jevtović, Saša ; Vuksanović, Ana ; Hajnšek, Sanja

engleski

Depression and quality of life in patients with epilepsy - single centre experience

Background: Patients with epilepsy commonly report depressive symptoms. The main aim of this study was to evaluate the relationship between epilepsy, antiepileptic drugs (AEDs) and depression. We also wanted to evaluate possible association between depressive symptofigms in patients with epilepsy with the quality of life (QoL). Material and methods: This was a prospective cross-sectional study carried out at the tertiary teaching hospital (University Hospital Centre Zagreb, Croatia) with Ethics committee approval. Questionnaires evaluating depressive symptoms and QoL were administered to consecutive patients treated in the Referral Centre of the Ministry of Health of the Republic of Croatia for Epilepsy. Depressive symptoms were evaluated using Hamilton Rating Scale for Depression (HAM-D17). Quality of life was assessed using Quality of life in epilepsy-31 inventory (QOLIE- 31) Background: Patients with epilepsy commonly report depressive symptoms. The main aim of this study was to evaluate the relationship between epilepsy, antiepileptic drugs (AEDs) and depression. We also wanted to evaluate possible association between depressive symptofigms in patients with epilepsy with the quality of life (QoL). Material and methods: This was a prospective cross-sectional study carried out at the tertiary teaching hospital (University Hospital Centre Zagreb, Croatia) with Ethics committee approval. Questionnaires evaluating depressive symptoms and QoL were administered to consecutive patients treated in the Referral Centre of the Ministry of Health of the Republic of Croatia for Epilepsy. Depressive symptoms were evaluated using Hamilton Rating Scale for Depression (HAM-D17). Quality of life was assessed using Quality of life in epilepsy-31 inventory (QOLIE-31) Results: 108 patients (63% women, 37% men ; mean age 39.54±15.91 years, range 18-80 years) with epilepsy were included. 14.8% of patients had focal, 35.2% generalised and 40.7% both types of epilepsy. Majority of patients (65.74%) were on two and more AEDs and quarter was on monotherapy (25%) ; 42% were on newer, 19% on older and 39% on both AEDs. Mean total score on HAM-D17 was 9.94±8.18 (men - mean total score 10.16±8.85, women - mean total score 9.81±7.84). There were no significant differences on HAM-D17 regarding gender and age. We didn't find statistically significant differences regarding AEDs (older vs. newer AEDs, or both types AEDs) and results on HAM-D17, nor between the type of epilepsy and results on HAM-D17. We found strong negative correlation between the higher QoL and HAM-D17 (p=0.000). Conclusions: Results of this study evaluating depressive symptoms in patients with epilepsy demonstrate that our patients mainly experience mild depressive symptoms, with no significant differences on HAM-D17 regarding gender and age. Patients with epilepsy with less pronounced depressive symptoms were found to have higher QoL. We did not find statistically significant differences regarding the type of epilepsy and results on HAM-D17, nor between the AEDs (older vs. newer AEDs, or both types AEDs) and results on HAM-D17.

epilepsy ; antiepileptic drugs ; depression ; quality of life

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Podaci o prilogu

486-489.

2021.

nije evidentirano

objavljeno

Podaci o matičnoj publikaciji

Psychiatria Danubina

0353-5053

1849-0867

Podaci o skupu

29th Danubian psychiatric symposium and IX Croatian congress on psychopharmacotherapy

predavanje

18.03.2021-20.03.2021

online ; Zagreb, Hrvatska

Povezanost rada

Kliničke medicinske znanosti

Poveznice
Indeksiranost