Pretražite po imenu i prezimenu autora, mentora, urednika, prevoditelja

Napredna pretraga

Pregled bibliografske jedinice broj: 1242700

Risks associated with prior oral anticoagulation use in hospitalized COVID-19 patients – A retrospective cohort study on 5392 patients from a tertiary centre


Bistrovic, Petra; Sabljic, Anica; Kovacevic, Ivona; Cikara, Tomislav; Keres, Tatjana; Lucijanic, Tomo; Mitrovic, Josko; Delic-Brkljacic, Diana; Manola, Sime; Lucijanic, Marko
Risks associated with prior oral anticoagulation use in hospitalized COVID-19 patients – A retrospective cohort study on 5392 patients from a tertiary centre // International Journal of Cardiology, 372 (2023), 144-149 doi:10.1016/j.ijcard.2022.11.051 (međunarodna recenzija, članak, znanstveni)


CROSBI ID: 1242700 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Risks associated with prior oral anticoagulation use in hospitalized COVID-19 patients – A retrospective cohort study on 5392 patients from a tertiary centre

Autori
Bistrovic, Petra ; Sabljic, Anica ; Kovacevic, Ivona ; Cikara, Tomislav ; Keres, Tatjana ; Lucijanic, Tomo ; Mitrovic, Josko ; Delic-Brkljacic, Diana ; Manola, Sime ; Lucijanic, Marko

Izvornik
International Journal of Cardiology (0167-5273) 372 (2023); 144-149

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Anticoagulant therapy ; Bleeding ; SARS-CoV-2 ; Survival ; Thrombosis

Sažetak
Introduction: There are conflicting data on prior oral-anticoagulant (OAC) use and outcomes of hospitalized COVID-19 patients. Due to uncertainties regarding associated risks with the prior OAC use, we have investigated this issue in a large cohort of hospitalized COVID- 19 patients from our institution. Methods: We have retrospectively evaluated a total of 5392 consecutive COVID-19 patients hospitalized in our tertiary center institution in period 3/2020 to 6/2021. Majority of patients received low-molecular-weight-heparin thromboprophylaxis and corticosteroids during hospitalization. Patients' characteristics and clinical outcomes were documented as a part of a hospital registry project and were evaluated according to the prior non-OAC, warfarin and direct oral anticoagulants (DOAC) use. Results: Median age was 72 years, median Charlson comorbidity index (CCI) was 4 points. There were 56.2% male patients. Majority of patients had severe (70.5%) or critical (15.8%) COVID-19 on admission. A total of 84.8% patients did not receive prior OAC, 9% were previously anticoagulated with warfarin and 6.2% were previously anticoagulated with DOACs. In the multivariate regression analyses, prior warfarin use was associated increased in-hospital mortality (OR 1.24, P = 0.048) independently of older age (OR 2.12, P < 0.001), male sex (OR 1.27, P < 0.001), higher CCI (OR 1.26, P < 0.001) and severe or critical COVID-19 on admission (OR 22.66, P < 0.001). Prior DOAC use was associated with higher occurrence of major bleeding (OR 1.72, P = 0.045) independently of higher CCI (OR 1.08, P = 0.017). Conclusion: Prior OAC use could be associated with worse clinical outcomes during COVID-19 hospitalization. These phenomena might be OAC type specific and persist after multivariate adjustments.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti



POVEZANOST RADA


Poveznice na cjeloviti tekst rada:

doi

Citiraj ovu publikaciju:

Bistrovic, Petra; Sabljic, Anica; Kovacevic, Ivona; Cikara, Tomislav; Keres, Tatjana; Lucijanic, Tomo; Mitrovic, Josko; Delic-Brkljacic, Diana; Manola, Sime; Lucijanic, Marko
Risks associated with prior oral anticoagulation use in hospitalized COVID-19 patients – A retrospective cohort study on 5392 patients from a tertiary centre // International Journal of Cardiology, 372 (2023), 144-149 doi:10.1016/j.ijcard.2022.11.051 (međunarodna recenzija, članak, znanstveni)
Bistrovic, P., Sabljic, A., Kovacevic, I., Cikara, T., Keres, T., Lucijanic, T., Mitrovic, J., Delic-Brkljacic, D., Manola, S. & Lucijanic, M. (2023) Risks associated with prior oral anticoagulation use in hospitalized COVID-19 patients – A retrospective cohort study on 5392 patients from a tertiary centre. International Journal of Cardiology, 372, 144-149 doi:10.1016/j.ijcard.2022.11.051.
@article{article, author = {Bistrovic, Petra and Sabljic, Anica and Kovacevic, Ivona and Cikara, Tomislav and Keres, Tatjana and Lucijanic, Tomo and Mitrovic, Josko and Delic-Brkljacic, Diana and Manola, Sime and Lucijanic, Marko}, year = {2023}, pages = {144-149}, DOI = {10.1016/j.ijcard.2022.11.051}, keywords = {Anticoagulant therapy, Bleeding, SARS-CoV-2, Survival, Thrombosis}, journal = {International Journal of Cardiology}, doi = {10.1016/j.ijcard.2022.11.051}, volume = {372}, issn = {0167-5273}, title = {Risks associated with prior oral anticoagulation use in hospitalized COVID-19 patients – A retrospective cohort study on 5392 patients from a tertiary centre}, keyword = {Anticoagulant therapy, Bleeding, SARS-CoV-2, Survival, Thrombosis} }
@article{article, author = {Bistrovic, Petra and Sabljic, Anica and Kovacevic, Ivona and Cikara, Tomislav and Keres, Tatjana and Lucijanic, Tomo and Mitrovic, Josko and Delic-Brkljacic, Diana and Manola, Sime and Lucijanic, Marko}, year = {2023}, pages = {144-149}, DOI = {10.1016/j.ijcard.2022.11.051}, keywords = {Anticoagulant therapy, Bleeding, SARS-CoV-2, Survival, Thrombosis}, journal = {International Journal of Cardiology}, doi = {10.1016/j.ijcard.2022.11.051}, volume = {372}, issn = {0167-5273}, title = {Risks associated with prior oral anticoagulation use in hospitalized COVID-19 patients – A retrospective cohort study on 5392 patients from a tertiary centre}, keyword = {Anticoagulant therapy, Bleeding, SARS-CoV-2, Survival, Thrombosis} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE


Citati:





    Contrast
    Increase Font
    Decrease Font
    Dyslexic Font