Antiplasmodial activity of harmirins – novel harmine-coumarin hybrids (CROSBI ID 730024)
Prilog sa skupa u zborniku | kratko priopćenje | međunarodna recenzija
Podaci o odgovornosti
Pavić, Kristina ; Rajić, Zrinka ; Pessanha de Carvalho, Lais ; Held, Jana
engleski
Antiplasmodial activity of harmirins – novel harmine-coumarin hybrids
Harmirins are hybrid compounds comprising both harmine and coumarin pharmacophores linked by 1, 2, 3-triazole. We have evaluated in vitro antiplasmodial activity against the erythrocytic stage of P. falciparum of five series of harmirins. Compound 12b showed the highest activity against the tested P. falciparum strains and the lowest cytotoxicity against non-cancer cell line Hek293.
harmine ; coumarin ; malaria ; Plasmodium
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Podaci o prilogu
407-408.
2022.
objavljeno
10.33320/maced.pharm.bull.2022.68.03.196
Podaci o matičnoj publikaciji
Macedonian Pharmaceutical Bulletin 68 (Suppl 1)
Glavas Dodov, Marija
Skopje: Macedonian Pharmaceutical Association
1409-8695
1857-8969
Podaci o skupu
7th Congress of Pharmacy in North Macedonia with international participation
poster
05.10.2022-09.10.2022
Ohrid, Sjeverna Makedonija
