engleski

ACUTE INFLUECE OF VARIOUS INTENSITY TRAINING ON CD14++CD16- MONOCYTES ACTIVATION

The benefits of regular physical activity are well known, but its effect on the immune response is not cleared yet. PURPOSE: The aim of this study is to determine the possible influence of various intensity training on acute pro-inflammatory monocyte activation. METHODS: Ten male recreative runners were tested, using the spiroergometric ramp test, to determine their individual gas exchange threshold (GET). Afterward the subjects were tested three times with three different intensitys (intensity GET, intensity GET– 10% and intensity GET +10%) and performed a 20-minute training during which the blood samples were collected. Using flow cytometry method blood samples were used to analyse CD14++CD16- monocytes activity. RESULTS: Results have shown that physical activity affects on pro-inflammatory monocytes activation, and that there is a connection between intensity and monocytes activation. Our results also suggested that time of blood sampling and the number of tested subjects have an influence on results. CONCLUSION: Recreative running with intensity around aerobic threshold affects CD14++CD16- monocytes activation. But for a better understanding of intensity influence, different blood sampling times and bigger samples should be considered

intensity GET, intensity GET– 10% and intensity GET +10%, CD14++CD16- monocytes

nije evidentirano