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Postoperative pain after root canal filling with bioceramic and epoxy resin based sealer – preliminary results of a randomized clinical study

Aim: To evaluate the occurence and intensity of postoperative pain in patients with periapical lesion after root canal filling with the bioceramic or epoxy resin based sealer. Methodology: This randomized clinical study (ClinicalTrials.gov ID:NCT04072926) included 40 patients with chronic apical periodontitis and previous root canal treatment. The patients were selected based on inclusion (asymptomatic previously treated teeth with periapical lesion larger than 5mm, sensitive to percussion and palpation) and exclusion criteria (immunocompromised patients, pregnancy, periodontally compromised teeth, signes of vertical root fracture, antibiotics usage in the last month). All selected patients received single-visit root canal retreatment by the same endodontist. After chemo-mechanical root canal instrumentation and 3% sodium hypochlorite irrigation, passive ultrasonic irrigation was used for final irrigation protocol. Then, the patients were randomly (using wheeldecide.com) divided into two groups based on the sealar used for single-cone filling: Group 1. Bioceramic sealer (BioRoot RCS) and epoxy resin based sealer (AH Plus). Every patient received a visual analog scale (VAS) to record occurence and pain intensity immediately after the retreatment and every next day during seven days and analgesic consumption. The results were analysed using Chisquare, Mann Whitney and Wicoxon tests with the level of significance 5%. Results: There was no significant difference in the occurence and intensity of postoperative pain, nor consumption of analgesics, between the bioceramic and epoxy resin based sealer (P < 0.05). Average duration of postoperative pain was 3 days, pain mostly started after 12h, and more then half of the patients felt no pain. Conclusion: Bioceramic and epoxy resin based sealer caused similar and low occurence and intensity of postoperative pain after single-visit root canal retreatment in patients with chronic periapical lesion.

Postoperative pain, root canal filling, bioceramic, epoxy resin

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