Impact of pharmacotherapeutic education on medication adherence and adverse outcomes in patients with type 2 diabetes mellitus: a prospective, randomized study (CROSBI ID 317113)
Prilog u časopisu | izvorni znanstveni rad
Podaci o odgovornosti
Marušić, Srećko ; Meliš, Petra ; Lucijanić, Marko ; Grgurević, Ivica ; Turčić, Petra ; Obreli Neto, Paulo Roque ; Bilić-Ćurčić, Ines
engleski
Impact of pharmacotherapeutic education on medication adherence and adverse outcomes in patients with type 2 diabetes mellitus: a prospective, randomized study
Aim: To evaluate the impact of pharmacotherapeutic education on 30-day post-discharge medication adherence and adverse outcomes in patients with type 2 diabetes mellitus (T2DM). Methods: The prospective, randomized, single- center study was conducted at the Medical Department of University Hospital Dubrava, Zagreb, between April and June 2018. One hundred and thirty adult patients with T2DM who were discharged to the community were randomly assigned to either the intervention or the control group. Both groups during the hospital stay received the usual diabetes education. The intervention group received additional individual pre-discharge pharmacotherapeutic education about the discharge prescriptions. Medication adherence and occurrence of adverse outcomes (adverse drug reactions, readmission, emergency department visits, and death) were assessed at the follow-up visit, 30 days after discharge. Results: The number of adherent patients was significantly higher in the intervention group (57/64 [89.9%] vs 41/61 [67.2%] ; χ2 test, P=0.003]. There was no significant difference between the groups in the number of patients who experienced adverse outcomes (31/64 [48.4%] vs 36/61 [59.0%] ; χ2 test, P=0.236). However, higher frequencies of all adverse outcomes were consistently observed in the control group. Conclusion: Pharmacotherapeutic education of patients with T2DM can significantly improve 30- day post-discharge medication adherence, without a significant reduction in adverse clinical outcomes.
diabetes ; education
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Podaci o izdanju
59 (6)
2018.
290-297
objavljeno
0353-9504
1332-8166
10.3325/cmj.2018.59.290
Povezanost rada
Biotehnologija u biomedicini (prirodno područje, biomedicina i zdravstvo, biotehničko područje), Javno zdravstvo i zdravstvena zaštita, Temeljne medicinske znanosti