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Pregled bibliografske jedinice broj: 1233978

Short-term outcomes of patients with chronic liver disease hospitalised with COVID-19


Grgurevic, Ivica; Lucijanić, Marko; Pastrovic, Frane; Barisic Jaman, Mislav; Tjesic Drinkovic, Ida; Zelenika, Marko; Milosevic, Marko; Medic, Barbara; Kardum, Dusko; Bokun, Tomislav et al.
Short-term outcomes of patients with chronic liver disease hospitalised with COVID-19 // Internal Medicine Journal, 52 (2022), 11; 1891-1899 doi:10.1111/imj.15817 (međunarodna recenzija, članak, znanstveni)


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Naslov
Short-term outcomes of patients with chronic liver disease hospitalised with COVID-19
(Short‐term outcomes of patients with chronic liver disease hospitalised with COVID‐19)

Autori
Grgurevic, Ivica ; Lucijanić, Marko ; Pastrovic, Frane ; Barisic Jaman, Mislav ; Tjesic Drinkovic, Ida ; Zelenika, Marko ; Milosevic, Marko ; Medic, Barbara ; Kardum, Dusko ; Bokun, Tomislav ; Luksic, Ivica ; Piskac Zivkovic, Nevenka ; Keres, Tatjana ; Grabovac, Vlatko ; Persec, Jasminka ; Barsic, Bruno

Izvornik
Internal Medicine Journal (1444-0903) 52 (2022), 11; 1891-1899

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
COVID-19, chronic liver disease, liver cirrhosis, prognosis, mortality

Sažetak
Background and aims: Patients with chronic liver disease (CLD) might have aggravated course upon acquisition of coronavirus disease 2019 (COVID- 19). We aimed to analyse the outcomes of patients with CLD who were hospitalized due to COVID-19. Methods: Medical records of 4014 patients hospitalized due to COVID-19 in a regional referral hospital over a 12-month period were analysed. Patients with CLD were identified based on discharge diagnoses according to ICD-10 classification. Patients were followed for 30 days from admission, and their outcomes (intensive care unit (ICU) admission, mechanical ventilation (MV) or death) were analysed. Results: Of the 4014 patients, 110 (2.7%) had CLD and 49 (1.2%) had cirrhosis. Median age of CLD patients was 67.5 years, 79 (71.8%) were males, 224 (23.5%) obese, 56 (50.9%) reported alcohol abuse, 24 (21.8%) had non-alcoholic fatty liver disease, 11 (10%) viral hepatitis and 98 (89.1%) had pneumonia. Median length of hospitalization was 12 days, 32 (29.1%) patients required ICU admission and 23 (20.9%) MV, while 43 (39.1%) died. In univariate analysis, patients with cirrhosis (45% vs 73%, HR=2.95 ; P<0.001), but not those with non-cirrhotic CLD (74% vs 73%, P>0.05), experienced worse 30-days survival when compared to age, sex and COVID-19 duration matched cohorts. In a logistic regression analysis conducted on the overall and matched cohorts, liver cirrhosis, but not CLD, predicted inferior survival independently of age, comorbidities and severity of COVID-19, with a fourfold higher adjusted risk of 30-day mortality. Conclusion: Cirrhosis is independently associated with higher 30-day mortality of hospitalized patients with COVID-19.

Izvorni jezik
Engleski

Poveznice na cjeloviti tekst rada:

doi onlinelibrary.wiley.com

Citiraj ovu publikaciju:

Grgurevic, Ivica; Lucijanić, Marko; Pastrovic, Frane; Barisic Jaman, Mislav; Tjesic Drinkovic, Ida; Zelenika, Marko; Milosevic, Marko; Medic, Barbara; Kardum, Dusko; Bokun, Tomislav et al.
Short-term outcomes of patients with chronic liver disease hospitalised with COVID-19 // Internal Medicine Journal, 52 (2022), 11; 1891-1899 doi:10.1111/imj.15817 (međunarodna recenzija, članak, znanstveni)
Grgurevic, I., Lucijanić, M., Pastrovic, F., Barisic Jaman, M., Tjesic Drinkovic, I., Zelenika, M., Milosevic, M., Medic, B., Kardum, D. & Bokun, T. (2022) Short-term outcomes of patients with chronic liver disease hospitalised with COVID-19. Internal Medicine Journal, 52 (11), 1891-1899 doi:10.1111/imj.15817.
@article{article, author = {Grgurevic, Ivica and Lucijani\'{c}, Marko and Pastrovic, Frane and Barisic Jaman, Mislav and Tjesic Drinkovic, Ida and Zelenika, Marko and Milosevic, Marko and Medic, Barbara and Kardum, Dusko and Bokun, Tomislav and Luksic, Ivica and Piskac Zivkovic, Nevenka and Keres, Tatjana and Grabovac, Vlatko and Persec, Jasminka and Barsic, Bruno}, year = {2022}, pages = {1891-1899}, DOI = {10.1111/imj.15817}, keywords = {COVID-19, chronic liver disease, liver cirrhosis, prognosis, mortality}, journal = {Internal Medicine Journal}, doi = {10.1111/imj.15817}, volume = {52}, number = {11}, issn = {1444-0903}, title = {Short-term outcomes of patients with chronic liver disease hospitalised with COVID-19}, keyword = {COVID-19, chronic liver disease, liver cirrhosis, prognosis, mortality} }
@article{article, author = {Grgurevic, Ivica and Lucijani\'{c}, Marko and Pastrovic, Frane and Barisic Jaman, Mislav and Tjesic Drinkovic, Ida and Zelenika, Marko and Milosevic, Marko and Medic, Barbara and Kardum, Dusko and Bokun, Tomislav and Luksic, Ivica and Piskac Zivkovic, Nevenka and Keres, Tatjana and Grabovac, Vlatko and Persec, Jasminka and Barsic, Bruno}, year = {2022}, pages = {1891-1899}, DOI = {10.1111/imj.15817}, keywords = {COVID-19, chronic liver disease, liver cirrhosis, prognosis, mortality}, journal = {Internal Medicine Journal}, doi = {10.1111/imj.15817}, volume = {52}, number = {11}, issn = {1444-0903}, title = {Short‐term outcomes of patients with chronic liver disease hospitalised with COVID‐19}, keyword = {COVID-19, chronic liver disease, liver cirrhosis, prognosis, mortality} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE


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