engleski

Advantages of exfoliative cytologic analysis and FNA biopsy in the diagnosis of malignant lymphoma in children

From 1979 to 1996 there were 89 cases of malignant lymphoma diagnosed at the Children's Hospital Zagreb, by cytological analysis.In this work the results of exofoliative or FNA cytologic diagnosos in 24 children are shown, because in this group it was the only possible method due to the severity of the clinical picture and the poor general condition of the children. In 19 children the results of exofoliative cytologic diagnosis were as folows: in nine children diagnosis was made by analysis of ascites: five were HL,and four were NHL. In ten children analysis of fluid pleural drain shown: eight NHL and two HL. In one child the diagnosis was made by analysis of the cerebrospinaL fluid: it was NHL. In four children the diagnosis was made by FNA biopsy. In three children the diagnosis was made by analysis of puncture ly<mphonode of the neck: in two children were HL, and in one child NHL. In one child the diagnosis was made by analysis of FNA biopsy node of the testicules: it was NHL. In the analysis of pleural drain and ascites immunologic phenotype confirmed the cytological analysis, and in some patientsd latter pathohistologicval diagnosis was confirmed by cytological diagnosis. The importance of exofoliative or FNA cytodiagnosis is stressed since sometimes it is the only possible method and also offers the possibility of immunologic and cytogenetic analysis.

Cytology; lymphoma; children

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