Circulating tumor cells in colorectal cancer: detection systems and clinical utility (CROSBI ID 316461)
Prilog u časopisu | pregledni rad (znanstveni) | međunarodna recenzija
Podaci o odgovornosti
Petrik, József ; Verbanac, Donatella ; Fabijanec, Marija ; Hulina-Tomašković, Andrea ; Čeri, Andrea ; Somborac-Bačura, Anita ; Petlevski, Roberta ; Grdić Rajković, Marija ; Rumora, Lada ; Krušlin, Božo ; Štefanović, Mario ; Ljubičić, Neven ; Baršić, Neven ; Hanžek, Antonija ; Bočkor, Luka ; Ćelap, Ivana ; Demirović, Alma ; Barišić, Karmela
engleski
Circulating tumor cells in colorectal cancer: detection systems and clinical utility
Colorectal cancer (CRC) is the third most common cancer worldwide. The high mortality from CRC is mainly related to metastasis affecting distant organs and their function. Dissemination of tumor cells from the primary tumor and hematogeneous spread are considered crucial in the formation of tumor metastases. The analysis of circulating tumor cells (CTCs) and CTC clusters in the blood can be used for the early detection of invasive cancer. Moreover, CTCs have a prognostic significance in the monitoring of a malignant disease or the response to chemotherapy. This work presents an overview of the research conducted on CTCs with the aim of finding suitable detection systems and assessing the possibility of clinical applications in patients with CRC.
colorectal cancer ; liquid biopsy ; circulating tumor cells ; CTC clusters ; viable CTCs ; isolation techniques ; detection methods ; clinical utility
nije evidentirano
nije evidentirano
nije evidentirano
nije evidentirano
nije evidentirano
nije evidentirano
Podaci o izdanju
23 (21)
2022.
13582
18
objavljeno
1422-0067
10.3390/ijms232113582
Trošak objave rada u otvorenom pristupu
Povezanost rada
Biotehnologija u biomedicini (prirodno područje, biomedicina i zdravstvo, biotehničko područje), Kliničke medicinske znanosti, Temeljne medicinske znanosti