Functional and molecular thyroid imaging (CROSBI ID 316095)
Prilog u časopisu | pregledni rad (stručni) | međunarodna recenzija
Podaci o odgovornosti
Giovanella, Luca ; Petranović Ovčariček, Petra
engleski
Functional and molecular thyroid imaging
Nuclear medicine methods were introduced in the 1940s for thyroid disease diagnosis and therapy. They is still a crucial part of thyroid nodules work-up. Thyroid imaging with iodine or iodine- analog isotopes is widely employed in patients with thyrotoxicosis and remains the only examination able to prove the presence of autonomously functioning thyroid tissue, which excludes malignancy with a high probability. In addition, technetium-99m-methoxyisobutylisonitrile ([99mTc]Tc-MIBI) scintigraphy and positron emission tomography/computed tomography (PET/CT) with 18F-fluoro-2-deoxy-d-glucose ([18F]FDG) are able to avoid unnecessary surgical procedures for cytologically inconclusive thyroid nodules, as confirmed by meta-analysis and cost- effectiveness studies. All considered thyroid molecular imaging allows functional characterization of different thyroid diseases, even before clinical symptoms become manifest, and remains integral to the management of such conditions. This paper summarizes main concepts of thyroid scintigraphy and its clinical use. In addition, it elaborates development of thyroid scintigraphy, as well as thyroid molecular imaging in patients with thyroid nodules and thyrotoxicosis.
Molecular imaging ; Hyperthyroidism ; Thyroid nodule
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Podaci o izdanju
66 (2)
2022.
86-92
objavljeno
1824-4785
1827-1936
10.23736/s1824-4785.22.03428-8
Povezanost rada
Kliničke medicinske znanosti