engleski

Effect of different diets on the lung fatty acid modification

The effect of dietary fat on the composition of lung fatty acids was studied in Fisher rats fed two experimental semisynthetic, isocaloric diets containing different quantities of fat (low fat diet (LFD) and medium-chain triacylglycerols diet (MCTD)). The effect of MCTs preparation on the lung phospho- and neutral lipids is manifested as a change in the degree of saturation expressed as a ratio of saturation index (RS(i)) MCTD vs. CD. The saturation increased: in neutral lipids by 70%, in phosphatidylcholine fraction by 152.6% and in other phospholipids by 39.5%. The results on the fatty acid composition of lipids obtained using LFD showed the effect of desaturation expressed as a ratio of desaturation index (RD(i)), in phosphatidylcholine fraction -1,95. The observed effect of desaturation was a consequence of the administered LFD, which contains a lower amount of essential fatty acids, which strongly affects the conversion of palmitic acid into palmitooleic acid. The LFD can be useful as a carbohydrate diet in a special clinical situation only if enriched with a certain amount of essential fatty acids, especially linoleic acid.

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