engleski

PLA in individualized augmentation scaffold – pilot study

Background: Various techniques have been developed for 3D reconstruction of the lost bone tissue, with currently the most widely used being titanium mesh replacement, the Khoury technique, and the distraction osteogenesis. All three techniques have significant disadvantages, narrow indication, and require exceptional operator skill. IBAM scaffold is made of biodegradable material, provide space for the formation of new bone tissue, and have the ability to be built into 3D complex individualized shapes. Aim / Hypothesis: The aim of the present study was to define the mechanical properties of 3D printed PLA material, to determine the stress distribution within the virtual test form–finite element method (FEA), and to compare the obtained stress values with the reference values. Material and Methods: In order to optimize the shape and mechanical characteristics of the biodegradable scaffold, the mechanical properties of 3D printed specimens were tested by finite element analysis (FEA) with different print orientations–horizontal, lateral and vertical. Also, the flexural strength and tensile strength of extruded PLA were tested on an Inspekt table 50 kN (Hegewald & Peschke Meß–und Prüftechnik GmbH). Results: The results of the FEA examination demonstrated higher values of tensile strength in the horizontal (32.98-35.53 MPa) and the lateral positions (26.97-29.69 MPa) compared to the vertical position (4.43-14.20 MPa). The horizontal position of the specimens also demonstrated the highest values when testing flexural strength, while during the impact strength testing the horizontal (0.40 J) and lateral positions (0.41 J) demonstrated double the values of the vertical position (0.2 J). Specimens of all tested orientations showed similar hardness values after 60s. Conclusion and Clinical implications: Based on the defined marginal loads of the model and the FEA, the results demonstrate that the planned arc geometry satisfies the criteria of the loads to which the scaffold will be exposed in the oral cavity. Mechanical properties of PLA meet the planned utilization of IBAM in computer-guided individualized bone augmentation. Biodegradable scaffolds will play a significant role in personalized patient care to provide predictable treatment options to enhance clinical outcomes.

CAD / CAM ; tissue engineering

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