engleski

Importance of vaccination in a patient presenting with cervical intraepithelial neoplasia CIN II

INTRODUCTION: Human papillomavirus (HPV) is sexually transmitted and one of the most common causes of viral infections of the reproductive tract. To this day it has been discovered more than 200 genotypes of HPV. They are divided into two groups of low and high risk. HPV infection with high-risk types is associated with the development of cervical intraepithelial neoplasia (CIN) and cervical cancer, but only if persistent HPV infection with oncogenic types is present.Vaccination against HPV prevents the development of CIN. CASE PRESENTATION: We present a 30-year-old woman who has not been vaccinated against HPV with CIN II. In March 2021, at her regular gynecology appointment, she was screened for precancers. The Pap test showed CIN II. Also, high-risk HPV was found. Control colposcopy showed that the squamocolumnar junction was not visible and the transformation zone was present. The examination also showed present acetowhite epithelium lesions on the anterior and posterior walls of the cervical canal. Three biopsy samples were taken and sent to pathology. Biopsy confirmed CIN II. In August 2021, the patient was hospitalized and conization was performed. Postoperative gynecological readings were good and regular check-up was advised. After treatment, HPV vaccination was recommended. CONCLUSION: Vaccination is also recommended for women who had been diagnosed with HPV infection. After conization, she was advised to get vaccinated with 9-valent vaccine against HPV, which she did. In this case, vaccination lowers the risk of recurrent CIN lesions after surgery in comparison to only surgery.

CIN II, HPV, vaccination

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