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Serum biochemical changes associated with cystic ovarian degeneration in pigs after atrazine treatment (CROSBI ID 101327)

Prilog u časopisu | izvorni znanstveni rad | međunarodna recenzija

Gojmerac, Tihomira ; Kartal, Božica, Ćurić, Stipica ; Žurić, Marijan ; Stjepan, Kušević ; Cvetnić, Željko Serum biochemical changes associated with cystic ovarian degeneration in pigs after atrazine treatment // Toxicology letters, 85 (1996), 1; 9-15. doi: 10.1016/0378-4274(96)03631-4

Podaci o odgovornosti

Gojmerac, Tihomira ; Kartal, Božica, Ćurić, Stipica ; Žurić, Marijan ; Stjepan, Kušević ; Cvetnić, Željko

engleski

Serum biochemical changes associated with cystic ovarian degeneration in pigs after atrazine treatment

Biochemical and histopathological parameters of the ovarian function were observed to asses the toxic effect of low dose of atrazin, an s-triazine herbicide, in female pigs (gilts) undergoing intensive breeding. Female pigs (cross-bred between Swedish and German landrace) received 2 mg atrazine kg-1 body wt. in feed daily during 19 days of the oestrus cycle. The last treatment day correspondent to day -3 of the on set of the next expected oestrus. Blood samples were collected 3 times daily at 3-h intervals on the first 5 post- treatment days. Serum 17B -oestradiol (17B-E) and progesterone (P) concentrations were determined. A significantly higher (P< 0.05 and P< 0.001, respectively) serum P concentration and significantly lower (P< 0.01 and 0.001, respectively) seru, m 17b-E concentration was recorded 48and 24 h before the onset of the next expected oestrus in atrazine-treated pigs, as compared to intact pigs. The onset of next expected oestrus failed to occur, but no other adverse clinical reactions associated with the treatment were recorded. Histopatological examination, of the ovaries of treted pigs indicated multiple ovarian follicular cysts and persistence of corpus luteum. Biochemmical and histopathological findings showed that subacute exposure of female pigs to low dose of atrazine their oestrus cycle.

s-Trazine herbicides ; atrazine ; toxicology ; reproduction

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nije evidentirano

nije evidentirano

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nije evidentirano

nije evidentirano

Podaci o izdanju

85 (1)

1996.

9-15

objavljeno

0378-4274

1879-3169

10.1016/0378-4274(96)03631-4

Povezanost rada

Šumarstvo

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