engleski

The association between blood pressure changes and outcome in acute stroke

Introduction The aim of this study is to establish the association between blood pressure (BP) changes and outcome in acute stroke (ischemic (ISH) and intracerebral haemorrhage (ICH)). Methods This prospective study included patients with severe stroke (ISH and ICH) admitted to intensive care unit within 6 hours after stroke onset. BP was measured every 2 hours during first 72 hours after stroke onset. Stroke severity and outcome was assessed using Scandinavian Stroke Scale at the time of admission (SSSa) and discharge (SSSd) from hospital. Results This study included 114 stroke patients (85 ISH and 29 ICH), mean age 73.1+12.9 years. Mean systolic BP at admission in ISH was 157+16.8mmHg, SSSa>16 had higher values. In ICH patients BP at admission was 163.4+19.3 mmHg, higher values were found in patients withSSSa<15.Systolic BP during first 72 hours was higher in ICH than in ISH patients (162.6mmHg ; 146.5mmHg, respectively). BP during first 72 hours in ICH group was continuously higher in patients &#8226 ; ; ; vho died and with SSSd<15 than in survivors with SSSd>16. Better outcome was observed in ISH patients with moderate nigher BP during first 72 than in patients with lower BP. SSSa was higher in ISH than in ICH patients. In ICH group 29% of patients died, but survivors had better SSSd than survi-. ors in ISH group. Conclusions: BP is important factor in prognosis of stroke &#8226 ; ; ; ourse and outcome. Moderate higher BP in ISH is associated with better outcome. In ICH patients, the problem was serious hyperpertension, often resistant to therapy.

acute stroke; blood pressure

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